Foot function in rheumatoid arthritis patients: a cross-sectional study

Clinical Rheumatology
Agnes Patricia de AndradeThelma Larocca Skare

Abstract

Rheumatoid arthritis (RA) is a chronic disease that affects mainly small joints from hands and feet. The aims of this study were to analyze the prevalence of foot involvement in a sample of Brazilian RA patients and to explore the influence of disease variables such as inflammatory activity, serological, and epidemiological profile in this type of involvement. One hundred RA patients and 100 healthy controls paired for gender, age, and body mass index answered the FFI-BR (Foot Functional Index-Brazilian version) that evaluates foot function. RA patients had epidemiological and clinical data collection upon direct questioning and chart review. C-reactive protein (CRP), ESR (erythrocyte sedimentation rate), and DAS28-ESR were used to measure disease activity. In the RA sample, 98% had foot pain versus 76% in the controls (p < 0.0001; OR = 15.4; 95% CI = 3.4-67.5); 96% had some difficulty in function versus 66% of controls (p < 0.0001; OR = 12.3; 95% CI = 4.1-36.5); and 73% had some incapacity versus 20% of controls (p < 0.0001; OR = 10.8; 95% CI = 5.5-20.9). Values of FFI-BR showed correlation with ESR (p = 0.006), CRP (p = 0.01), and DAS28-ESR (p < 0.0001). No association between FFI-BR total score and gender, ethnic background,...Continue Reading

References

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Mar 23, 2017·Rheumatology International·Minna StoltHelena Leino-Kilpi

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Citations

Nov 25, 2020·Disability and Rehabilitation·Ana Belen Ortega-AvilaGabriel Gijon-Nogueron
May 20, 2020·BMJ Open·Andres Reinoso-CoboAna Belen Ortega-Avila
Apr 4, 2021·International Journal of Environmental Research and Public Health·Jose Alberto Sanchez-CastilloAna Belen Ortega-Avila
Jun 3, 2021·International Journal of Environmental Research and Public Health·María Reina-BuenoInmaculada C Palomo-Toucedo
Oct 15, 2021·Journal of Empirical Research on Human Research Ethics : JERHRE·Minna StoltHelena Leino-Kilpi

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