Jan 1, 1975

Force development of isoproterenol-damaged frog heart muscle in cyanide anoxia

Recent Advances in Studies on Cardiac Structure and Metabolism
A Carlsten, O Poupa

Abstract

From recent experiments it is indicated that in frogs living at +25 degrees C the abnormal response to cyanide anoxia appears as soon as 4-5 hr after the first isoproterenol (IPR) injection, but the aneurysm does not appear until a few hours after the second injection of IPR. There is evidently a discrepancy between the biochemical and structural effects of IPR on the heart. The biochemical effects are probably transient as we have observed that a normal response to cyanide reappears a few weeks after the second IPR injection. It might thus be concluded that IPR causes derangement to the cells also in hearts without any visible lesions and demonstrated as a lowered resistance to histotixic anoxia. This effect precedes any structural damage if such should occur and is of a transient nature.

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Rana pipiens
Myocardial Contraction
Salientia
Aneurysm
Isocyanides
Myocardium
Carbonic Acid Ions
Anoxemia
Novodrin
Heart

About this Paper

Related Feeds

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.

Related Papers

Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Section A, Pathology
A CarlstenO Poupa
Acta Pathologica Et Microbiologica Scandinavica. Section A, Pathology
A CarlstenO Poupa
Recent Advances in Studies on Cardiac Structure and Metabolism
L SullivanL Lindström
© 2020 Meta ULC. All rights reserved