Force-frequency relationship in the echocardiography laboratory: a noninvasive assessment of Bowditch treppe?

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
Tonino BombardiniEugenio Picano

Abstract

Estimation of contractility of the left ventricle is an important, and as yet elusive, goal with noninvasive techniques. We sought to assess the feasibility of a totally noninvasive estimation of force-frequency relation (FFR) during exercise stress in the echocardiography laboratory. We enrolled 13 healthy control patients (12 men, age 38 +/- 15 years) as group I, and 50 patients (38 men, age 64 +/- 11 years) referred for exercise echocardiography as group II. To build the FFR, the force was determined at each step as the ratio of the systolic pressure (cuff sphygmomanometer)/end-systolic volume index (biplane Simpson's rule/body surface area). The slope of the relationship was calculated with the linear best fit of the FFR. Noninvasive systolic pressure/end-systolic volume ratio was obtained in all patients. The slope of the linear best fit of the force-frequency curve was lower in group II compared with group I (group II = 10.1 +/- 9.3 x 10(-2) vs group I = 14.9 +/- 9.9 x 10(-2) group I, P =.04). By regional wall-motion analysis, 2 subgroups were identified in group II: group IIA (n = 8) had a positive echocardiogram; and group IIB (n = 42) had a negative echocardiogram. The slope of the force-frequency curve was lower in pa...Continue Reading

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Citations

Apr 13, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Hansjuergen BondkeGert Baumann
Nov 20, 2013·Cardiovascular Ultrasound·Tonino BombardiniEugenio Picano
Dec 13, 2005·Cardiovascular Ultrasound·Suzana Gligorova, Marco Agrusta
Jan 26, 2006·Cardiovascular Ultrasound·Giorgio ArpesellaEugenio Picano
Nov 16, 2010·Cardiovascular Ultrasound·Tonino BombardiniEugenio Picano
Oct 16, 2013·European Heart Journal·Eugenio Picano, Patricia A Pellikka
Mar 29, 2011·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Tonino BombardiniEugenio Picano
Dec 8, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Quirino CiampiRosa Sicari
Feb 6, 2010·Pacing and Clinical Electrophysiology : PACE·Vincenzo GemignaniTonino Bombardini
Feb 11, 2005·European Journal of Heart Failure·Tonino BombardiniEugenio Picano
May 25, 2010·Circulation. Cardiovascular Imaging·Christine L JellisThomas H Marwick
Apr 13, 2018·Minerva cardioangiologica·Eugenio PicanoQuirino Ciampi
Apr 13, 2019·The International Journal of Cardiovascular Imaging·Marco A R TorresUNKNOWN Stress Echo 2020 study group of the Italian Society of Cardiovascular Imaging
Jul 3, 2021·Journal of Clinical Medicine·Tonino Bombardini On Behalf Of The Stress Echo Study Group Of The Italian Society Of Cardiovascular Imaging
Nov 18, 2021·The International Journal of Cardiovascular Imaging·Antonella MeloniAlessia Pepe

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