Forearm training reduces the exercise pressor reflex during ischemic rhythmic handgrip

Journal of Applied Physiology
S Mostoufi-MoabL I Sinoway

Abstract

We examined the effects of unilateral, nondominant forearm training (4 wk) on blood pressure and forearm metabolites during ischemic and nonischemic rhythmic handgrip (30 1-s contractions/min at 25% maximal voluntary contraction). Contractions were performed by 10 subjects with the forearm enclosed in a pressurized Plexiglas tank to induce ischemic conditions. Training increased the endurance time in the nondominant arm by 102% (protocol 1). In protocol 2, tank pressure was increased in increments of 10 mmHg/min to +50 mmHg. Training raised the positive-pressure threshold necessary to engage the pressor response. In protocol 3, handgrip was performed at +50 mmHg and venous blood samples were analyzed. Training attenuated mean arterial pressure (109 +/- 5 and 98 +/- 4 mmHg pre- and posttraining, respectively, P < 0.01), venous lactate (2.9 +/- 0.4 and 1.8 +/- 0.3 mmol/l pre- and posttraining, respectively, P < 0.01), and the pH response (7.21 +/- 0.02 and 7.25 +/- 0.01, pre- and posttraining, respectively, P < 0.01). However, deep venous O2 saturation was unchanged. Training increased the positive-pressure threshold for metaboreceptor engagement, reduced metabolite concentrations, and reduced mean arterial pressure during ischem...Continue Reading

References

Sep 1, 1977·The Journal of Physiology·P Andersen, J Henriksson
Jun 1, 1992·The Journal of Clinical Investigation·L I SinowayA L Mark
Oct 1, 1991·Journal of Applied Physiology·D SilberL Sinoway
Mar 1, 1990·Journal of Applied Physiology·D M RottoM P Kaufman
Aug 1, 1990·Journal of Applied Physiology·L B Rowell, D S O'Leary
Apr 1, 1990·Journal of Applied Physiology·M J JoynerJ T Shepherd
May 1, 1989·Journal of Applied Physiology·D R Seals
Jan 1, 1989·Journal of Applied Physiology·L SinowayR Zelis
Jun 1, 1988·Journal of Applied Physiology·D M Rotto, M P Kaufman
Oct 1, 1988·The Journal of Clinical Investigation·R G VictorR L Nunnally
Feb 1, 1987·Journal of Applied Physiology·P G SnellC G Blomqvist
Feb 1, 1987·Pflügers Archiv : European journal of physiology·B C MacielL E Martins
Jul 1, 1974·The Journal of Clinical Investigation·C E MartinJ J Leonard
Jun 1, 1970·Journal of Applied Physiology·U Freyschuss
Jun 1, 1969·The American Journal of Physiology·P D Gollnick, D W King
Mar 1, 1984·Pflügers Archiv : European journal of physiology·F ThimmE Meier zu Verl
Apr 1, 1982·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·K KlausenJ Trap-Jensen
Mar 1, 1994·Journal of Applied Physiology·B A BatmanL I Sinoway
Mar 1, 1994·The Journal of Physiology·J W WilliamsonN H Secher
Apr 1, 1994·The Journal of Clinical Investigation·F Costa, I Biaggioni
Oct 1, 1996·Journal of Applied Physiology·L SinowayU Leuenberger

❮ Previous
Next ❯

Citations

May 8, 1999·Journal of Applied Physiology·C A Ray
Jul 15, 2015·American Journal of Physiology. Heart and Circulatory Physiology·Masaki MizunoScott A Smith
Jan 1, 2017·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Amanda J MillerUrs A Leuenberger
Aug 21, 2019·Experimental Physiology·Richard M BruceMichael J White
Jul 2, 2003·Journal of Applied Physiology·Joseph C DaleyLawrence I Sinoway
Sep 15, 2004·Experimental Physiology·James P Fisher, Michael J White
Jun 29, 2018·European Journal of Applied Physiology·Patrik SundbladThomas Gustafsson
Feb 6, 2003·Medicine and Science in Sports and Exercise·Andrea C TaylorRonald L Wiley
Feb 17, 2007·Pacing and Clinical Electrophysiology : PACE·Melanie BarantkeHendrik Bonnemeier
Sep 15, 2007·The Journal of Physiology·Jonathan D WittA William Sheel
Mar 15, 2011·Journal of Sports Sciences·Gavin R DevereuxIan Swaine
Sep 6, 2015·Current Hypertension Reports·Poghni Peri-OkonnyWanpen Vongpatanasin
Oct 8, 2013·Physiological Reports·Matthew D MullerLawrence I Sinoway
Oct 17, 2017·American Journal of Physiology. Heart and Circulatory Physiology·Joel D TrinityRussell S Richardson
Jul 1, 2021·European Journal of Applied Physiology·Gabriel GamaJuliana Pereira Borges
Oct 26, 2005·Respiratory Medicine·Francesco GigliottiGiorgio Scano

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.