Forebrain projections to brainstem nuclei involved in the control of mandibular movements in rats

European Journal of Oral Sciences
Marcelo Betti MascaroCarol Fuzeti Elias

Abstract

Mandibular movements occur through the triggering of trigeminal motoneurons. Aberrant movements by orofacial muscles are characteristic of orofacial motor disorders, such as nocturnal bruxism (clenching or grinding of the dentition during sleep). Previous studies have suggested that autonomic changes occur during bruxism episodes. Although it is known that emotional responses increase jaw movement, the brain pathways linking forebrain limbic nuclei and the trigeminal motor nucleus remain unclear. Here we show that neurons in the lateral hypothalamic area, in the central nucleus of the amygdala, and in the parasubthalamic nucleus, project to the trigeminal motor nucleus or to reticular regions around the motor nucleus (Regio h) and in the mesencephalic trigeminal nucleus. We observed orexin co-expression in neurons projecting from the lateral hypothalamic area to the trigeminal motor nucleus. In the central nucleus of the amygdala, neurons projecting to the trigeminal motor nucleus are innervated by corticotrophin-releasing factor immunoreactive fibers. We also observed that the mesencephalic trigeminal nucleus receives dense innervation from orexin and corticotrophin-releasing factor immunoreactive fibers. Therefore, forebrain ...Continue Reading

References

Aug 15, 1978·Experimental Brain Research·D A Hopkins, G Holstege
Apr 15, 1992·Biological Psychiatry·A MedaliaI H Scheinberg
Jul 1, 1988·Brain Research Bulletin·Y TakeuchiR Matsushima
Nov 1, 1983·The Journal of Comparative Neurology·J B Travers, R Norgren
Sep 13, 1994·Proceedings of the National Academy of Sciences of the United States of America·E PotterW Vale
Feb 15, 1993·The Journal of Comparative Neurology·S de LacalleC B Saper
Dec 28, 1995·Brain Research. Molecular Brain Research·S SashiharaS G Waxman
May 30, 1998·Journal of Neuroscience Methods·T SaitoT Nemoto
Oct 31, 2000·Neuron·T C ThannickalJ M Siegel
Dec 5, 2000·Regulatory Peptides·N J DunJ K Chang
Jun 15, 2001·The Journal of Comparative Neurology·P LuoD Dessem
Oct 30, 2001·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·J M SiegelR Nienhuis
Mar 5, 2002·Journal of Oral Rehabilitation·F Lobbezoo, M Naeije
May 24, 2003·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·G J LavigneB J Sessle
Oct 15, 1960·The Japanese Journal of Physiology·Y KAWAMURA, S TSUKAMOTO
Feb 3, 2004·The Journal of Comparative Neurology·Marina Goto, Larry W Swanson
Jul 22, 2004·British Journal of Pharmacology·Anna CastañéOlga Valverde
Jun 28, 2005·Neuroscience Letters·Marcelo Betti MascaroCarol Fuzeti Elias
Jul 15, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Maan Gee LeeBarbara E Jones
Jul 6, 2006·The European Journal of Neuroscience·Rutger KuipersGert Holstege
Feb 23, 2007·Archives of Oral Biology·Gilles J LavigneBarry Sessle
Apr 5, 2007·Brain Research·Masaaki YamamotoAtsushi Yoshida

❮ Previous
Next ❯

Citations

Sep 1, 2012·International Journal of Oral Science·Michelle Alicia OmmerbornRalf Schäfer
Sep 21, 2011·Brain : a Journal of Neurology·Giuseppe PlazziKailash P Bhatia
Oct 22, 2013·Brain : a Journal of Neurology·Fabio PizzaGiuseppe Plazzi
Apr 11, 2012·The Journal of Comparative Neurology·Joel D Hahn, Larry W Swanson
Dec 17, 2014·Neuroscience and Biobehavioral Reviews·Bo HuJun Zhang
Mar 14, 2014·Brain Structure & Function·Eric ErbsDominique Massotte
Oct 27, 2011·PloS One·Lino BecerraDavid Borsook

❮ Previous
Next ❯

Related Concepts

Related Feeds

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.