Forehead electrodes sufficiently detect propofol-induced slow waves for the assessment of brain function after cardiac arrest.

Journal of Clinical Monitoring and Computing
Jukka KortelainenTero Ala-Kokko

Abstract

In a recent study, we proposed a novel method to evaluate hypoxic ischemic encephalopathy (HIE) by assessing propofol-induced changes in the 19-channel electroencephalogram (EEG). The study suggested that patients with HIE are unable to generate EEG slow waves during propofol anesthesia 48 h after cardiac arrest (CA). Since a low number of electrodes would make the method clinically more practical, we now investigated whether our results received with a full EEG cap could be reproduced using only forehead electrodes. Experimental data from comatose post-CA patients (N = 10) were used. EEG was recorded approximately 48 h after CA using 19-channel EEG cap during a controlled propofol exposure. The slow wave activity was calculated separately for all electrodes and four forehead electrodes (Fp1, Fp2, F7, and F8) by determining the low-frequency (< 1 Hz) power of the EEG. HIE was defined by following the patients' recovery for six months. In patients without HIE (N = 6), propofol substantially increased (244 ± 91%, mean ± SD) the slow wave activity in forehead electrodes, whereas the patients with HIE (N = 4) were unable to produce such activity. The results received with forehead electrodes were similar to those of the full EEG ca...Continue Reading

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Citations

Oct 16, 2020·Journal of Neural Engineering·Nooshin BahadorJukka Kortelainen
Jul 16, 2021·Resuscitation·Janneke Horn, Myrthe van Merkerk

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Methods Mentioned

BETA
sedation

Software Mentioned

Matlab
EEGLAB

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