Forensic parameters and admixture in Mestizos from five geographic regions of Mexico based on 20 autosomal STRs (Powerplex 21 system)

International Journal of Legal Medicine
J A Aguilar-VelázquezH Rangel-Villalobos

Abstract

We analyzed Mestizo (admixed) population samples from different geographic regions of Mexico (n = 1283) with 20 autosomal STRs (PowerPlex® 21, Promega Corp.). Allele frequencies and forensic parameters from the Northwest, Northeast, West, Center, and Southeast regions are reported, as well as from the pooled Mexican population sample. The combined PD and PE for this 20 STR system were > 0.9999999999 and > 0.99999996593% in all five population samples, respectively. Analysis of molecular variance (AMOVA) of these Mexican population samples, plus Monterrey (Northeast) and Mexico (Center) Cities, showed low but significant differences among Mexican-Mestizos from the seven populations (Fst = 0.20%; p = 0.0000). Structure analysis showed the highest proportion of Native American ancestry in Mexico City, Center, and Southeast regions, respectively, which was in agreement with the estimated genetic distances represented in a MDS plot and a NJ tree. The best fit of population clusters (K = 4) obtained with the Structure software indicates that Mexican-Mestizos are mainly composed by European, African, and two Native American ancestries. The European and Native American ancestries displayed a contrary gradient, increasing toward the Nor...Continue Reading

References

Jan 14, 2009·American Journal of Physical Anthropology·Rodrigo Rubi-CastellanosHéctor Rangel-Villalobos
May 13, 2009·Proceedings of the National Academy of Sciences of the United States of America·Irma Silva-ZolezziGerardo Jimenez-Sanchez
Dec 2, 2009·Forensic Science International. Genetics·Andreas O TillmarKerstin Montelius
May 14, 2011·Molecular Ecology Resources·Laurent Excoffier, Heidi E L Lischer
Mar 13, 2014·Forensic Science International. Genetics·Erika Ramírez-FloresLourdes Vega-Navarrete
Dec 2, 2014·Homo : internationale Zeitschrift für die vergleichende Forschung am Menschen·J Salazar-FloresH Rangel-Villalobos
Feb 17, 2015·Molecular Ecology Resources·Naama M KopelmanItay Mayrose
Apr 7, 2016·International Journal of Legal Medicine·J A Aguilar-VelázquezH Rangel-Villalobos

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Citations

Jan 16, 2019·Annals of Human Biology·José Alonso Aguilar-VelázquezHéctor Rangel-Villalobos
Nov 11, 2019·International Journal of Legal Medicine·Yadira Lizethe López-RamírezHéctor Rangel-Villalobos

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