Foresight beats hindsight: The neural correlates underlying motor preparation in the pro-/anti-cue paradigm

Brain and Behavior
Franziska EmmerlingAlexander T Sack

Abstract

Human motor behaviors are characterized by both, reactive and proactive mechanisms. Yet, studies investigating the neural correlates of motor behavior almost exclusively focused on reactive motor processes. Here, we employed the pro-/anti-cue motor preparation paradigm to systematically study proactive motor control in an imaging environment. In this paradigm, either pro- or anti-cues are presented in a blocked design. Four fingers (two from each hand) are mapped onto four visual target locations. Visual targets require a speeded response by one corresponding finger, but, most importantly, they are preceded by visual cues that are congruent ("pro-cue"), incongruent ("anti-cue"), or neutral with respect to the responding hand. With short cue-target intervals, congruence effects are based on automatic motor priming of the correct hand (in case of pro-cues) or incorrect hand (in case of anti-cues), generating, respectively, reaction time benefits or reaction time costs relative to the neutral-cue. With longer cue-target intervals, slower top-down processes become effective, transforming early anti-cue interference into late anti-cue facilitation. We adapted this paradigm to be compatible with neuroimaging, tested and validated it ...Continue Reading

References

Feb 1, 1980·The Quarterly Journal of Experimental Psychology·M I Posner
May 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S D FormanD C Noll
Mar 4, 2000·Nature Neuroscience·J B HopfingerG R Mangun
Feb 15, 2001·Human Brain Mapping·V MenonA L Reiss
May 8, 2002·Nature Reviews. Neuroscience·Maurizio Corbetta, Gordon L Shulman
May 15, 2003·Current Opinion in Neurobiology·Jeffrey D Schall
Jun 20, 2003·NeuroImage·R DeichmannR Turner
Oct 24, 2003·Journal of Neurophysiology·Steve W KennerleyM F S Rushworth
Feb 21, 2004·Nature Reviews. Neuroscience·Douglas P Munoz, Stefan Everling
Mar 31, 2004·Trends in Cognitive Sciences·Adam R AronRussell A Poldrack
May 6, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·J Michelle KincadeMaurizio Corbetta
Mar 4, 2006·Journal of Cognitive Neuroscience·Christopher D ChambersJason B Mattingley
Dec 23, 2006·NeuroImage·Tilmann A KleinMarkus Ullsperger
Oct 2, 2007·NeuroImage·Derek Evan NeeMarc G Berman
Oct 19, 2007·Journal of Neurophysiology·Christopher D ChambersJason B Mattingley
Jul 1, 2008·NeuroImage·Magali JaffardPhilippe Boulinguez
Oct 7, 2008·Neuroscience and Biobehavioral Reviews·Christopher D ChambersMark A Bellgrove
Mar 12, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Julie DuqueRichard B Ivry
Jul 16, 2010·Proceedings of the National Academy of Sciences of the United States of America·Frederick VerbruggenChristopher D Chambers
Nov 5, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Xiaomo ChenVeit Stuphorn
Jan 26, 2011·Attention, Perception & Psychophysics·Lynn Huestegge, Jos J Adam
Jun 14, 2012·Psychological Science·Frederick VerbruggenChristopher D Chambers
Jun 23, 2012·Frontiers in Neuroengineering·Veit Stuphorn, Erik E Emeric
Aug 29, 2012·The European Journal of Neuroscience·Claire WardakSuliann Ben Hamed
Sep 4, 2013·Neuroscience and Biobehavioral Reviews·Joy J Geng, Simone Vossel
May 20, 2014·Social Cognitive and Affective Neuroscience·Franziska DambacherTeresa Schuhmann
Oct 7, 2014·The Cerebellum·Silvia Picazio, Giacomo Koch
Feb 24, 2015·Behavior Research Methods·Leendert van MaanenAndrew Heathcote
Nov 5, 2015·Nature Reviews. Neuroscience·Marjan JahanshahiJosé A Obeso

❮ Previous
Next ❯

Citations

Nov 21, 2020·Acta Psychologica·Jos J Adam, Pascal W M Van Gerven

❮ Previous
Next ❯

Software Mentioned

SPSS Statistics
FMRI
Brain Voyager QX

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.