Formaldehyde as an alternative to antibiotics for treatment of refractory impetigo and other infectious skin diseases

Expert Review of Anti-infective Therapy
Philip NikolicJohn Whitehall

Abstract

Introduction: Antibiotic-resistant strains of bacteria are an increasing problem in hospitals and in the community. This has resulted in bacterial infections such as impetigo becoming difficult to treat. Alternative treatment options are needed. Areas covered: In this paper, a past study that assessed the health burden of scabies in North Queensland is described and from it, the potential for formaldehyde as an alternative antimicrobial treatment is discussed. In doing so, antibiotic resistance, impetigo, permethrin, and formaldehyde are introduced and the current understanding and limitations of the effects of formaldehyde on humans are outlined. The limited cases of formaldehyde resistance in bacteria are also discussed. Expert opinion: Formaldehyde is currently used as a preservative in cosmetics and medicinal creams due to its antibacterial activity. It, therefore, has the potential to be used as an alternative antibacterial treatment for infections with antibiotic-resistant bacteria. The harmful side effects of airborne formaldehyde and exposure in allergic individuals have been extensively studied. Significantly less research has been conducted on formaldehyde skin contact in healthy individuals. If formaldehyde is safe f...Continue Reading

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Citations

May 10, 2020·MicrobiologyOpen·Philip NikolicJohn Whitehall
May 8, 2021·Journal of the European Academy of Dermatology and Venereology : JEADV·H S KimG Yosipovitch

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