PMID: 6413850Sep 1, 1983Paper

Formaldehyde mutagenesis in Drosophila. Molecular analysis of ADH-negative mutants

Mutation Research
C BenyajatiW Sofer

Abstract

The Adh gene from 4 formaldehyde-generated ADH-negative mutants of Drosophila melanogaster has been cloned and sequenced. All 4 mutants bear small deletions within the gene, ranging in size from 6 to 34 base pairs. 2 of the deletions lie within a 65-base pair intervening sequence and are accompanied by other aberrations. The other two are within the protein coding region of the gene. Some of these aberrations may be explained by a slipped mispairing mechanism.

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