Formaldehyde, Oxidative Stress, and FeNO in Traffic Police Officers Working in Two Cities of Northern Italy

International Journal of Environmental Research and Public Health
Giulia SquillaciotiRoberto Bono

Abstract

Personal air formaldehyde (air-FA) was measured as risk factor of airways inflammation and oxidative stress (SO) induction. Overall, 154 police officers were enrolled from two differently urbanised Italian cities, Turin and Pavia. Urinary F2t-isoprostane (15-F2t-IsoP), a prostaglandin-like compound, was quantified as a biomarker of general OS in vivo and fractional exhaled nitric oxide (FeNO) was measured for monitoring local inflammatory processes. Urinary cotinine was quantified as a biomarker of tobacco smoking exposure. Traffic police officers living in Turin showed an increased level of log air-FA (p < 0.001), equal to +53.6% (p < 0.001). Log air-(FA) mean values were 3.38 (C.I. 95% 3.33-3.43) and 2.84 (C.I. 95% 2.77-2.92) in Turin and Pavia, respectively. Log (air-FA) was higher in "outdoor workers" (3.18, C.I. 95% 3.13-3.24, p = 0.035) compared to "indoor workers", showing an increase of +9.3%, even controlling for sex and city. The analyses on 15-F2t-IsoP and FeNO, both adjusted for log air-FA, highlighted that OS and inflammation were higher (+66.8%, p < 0.001 and +75%, p < 0.001, respectively) in Turin traffic police officers compared to those from Pavia. Our findings suggest that even low exposures to traffic-related...Continue Reading

References

Oct 1, 1969·Clinica Chimica Acta; International Journal of Clinical Chemistry·H Bartels, M Cikes
Jan 24, 2003·Scandinavian Journal of Work, Environment & Health·Anne MaîtreRégis de Gaudemaris
Apr 9, 2005·American Journal of Respiratory and Critical Care Medicine·UNKNOWN American Thoracic Society, UNKNOWN European Respiratory Society
Jun 29, 2007·Respiration; International Review of Thoracic Diseases·Luisa BommaritoUNKNOWN ECRHS Turin, Italy Study Group
Jul 3, 2007·Mutation Research·A C BulmerK-H Wagner
Jan 13, 2010·Environmental Health Perspectives·Gerald McGwinJohn I Kennedy
Jan 26, 2010·Environment International·Roberto BonoRenato Rovere
Jul 27, 2011·Mutation Research·Anh DuongLuoping Zhang
Sep 3, 2011·American Journal of Respiratory and Critical Care Medicine·Raed A DweikUNKNOWN American Thoracic Society Committee on Interpretation of Exhaled Nitric Oxide Levels (FENO) for Clinical Applications
Sep 26, 2013·International Journal of Hygiene and Environmental Health·S S YamamotoA A Malik
Mar 19, 2014·Chinese Journal of Cancer·Wei ZhangYi-Xin Zeng
Mar 19, 2014·Environmental Research·Natália BruckerSolange C Garcia
Apr 4, 2014·Environmental Health Perspectives·Alessandro MarconRoberto de Marco
Mar 3, 2015·European Respiratory Review : an Official Journal of the European Respiratory Society·Ulugbek B NurmatovAziz Sheikh
Aug 30, 2017·Environmental Pollution·Amit U RaysoniWen-Whai Li
Mar 14, 2018·The Science of the Total Environment·Md Aynul Bari, Warren B Kindzierski
Feb 26, 2016·Toxicology Research·Roberto BonoMarco E M Peluso
Feb 20, 2019·Nitric Oxide : Biology and Chemistry·M Bobrowska-KorzeniowskaW Stelmach
Mar 16, 2019·Annals of Global Health·Regina Montero-MontoyaOmar Arellano-Aguilar
Apr 2, 2019·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Elisabet NerpinUNKNOWN European Community Respiratory Health Survey (ECRHS) study group
Apr 3, 2019·Environmental Research·Roberto BonoMarco Peluso
Dec 28, 2019·International Journal of Environmental Research and Public Health·Giulia SquillaciotiRoberto Bono

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Citations

Mar 14, 2021·Environmental Research·Samuele De PetrisEnrico Borgogno-Mondino

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BETA
ELISA

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STATA SE

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