Formaldehyde-releasers in cosmetics: relationship to formaldehyde contact allergy. Part 1. Characterization, frequency and relevance of sensitization, and frequency of use in cosmetics

Contact Dermatitis
Anton C de GrootPieter-Jan Coenraads

Abstract

In this part of a series of review articles on formaldehyde-releasers and their relationship to formaldehyde contact allergy, formaldehyde-releasers in cosmetics are discussed. In this first part of the article, key data are presented including frequency of sensitization and of their use in cosmetics. In Europe, low frequencies of sensitization have been observed to all releasers: 2-bromo-2-nitropropane-1,3-diol 0.4-1.2%, diazolidinyl urea 0.5-1.4%, imidazolidinyl urea 0.3-1.4%, quaternium-15 0.6-1.9% (for DMDM hydantoin no recent data are available). All releasers score (far) higher prevalences in the USA; the possible explanations for this are discussed. The relevance of positive patch test reactions has been insufficiently investigated. In the USA, approximately 20% of cosmetics and personal care products (stay-on products: 17%, rinse-off products 27%) contain a formaldehyde-releaser. The use of quaternium-15 is decreasing. For Europe, there are no comparable recent data available. In the second part of the article, the patch test relationship of the releasers in cosmetics to formaldehyde contact allergy will be reviewed and it will be assessed whether products preserved with formaldehyde-releasers may contain enough free fo...Continue Reading

References

Nov 1, 1990·Contact Dermatitis·W AbererG Gailhofer
Jan 1, 1990·Contact Dermatitis·P J FroschJ D Wilkinson
Jan 1, 1989·Archives of Dermatological Research·C M Perret, R Happle
Apr 1, 1988·Contact Dermatitis·A C de GrootJ W Weyland
Oct 1, 1986·Contact Dermatitis·A C de GrootJ W Weyland
Feb 1, 1983·Journal of the American Academy of Dermatology·F J Storrs, D E Bell
Oct 1, 1995·Contact Dermatitis·M C JacobsN Taub
Sep 1, 1996·Contact Dermatitis·B KränkeW Aberer
Mar 14, 1998·Acta Dermato-venereologica·B GruvbergerM Tammela
Oct 15, 1998·Contact Dermatitis·A GoossensE Put
Feb 17, 2000·Archives of Dermatology·J G MarksJ S Taylor
Sep 14, 2000·Contact Dermatitis·M P Shaffer, D V Belsito
Jan 5, 2001·Contact Dermatitis·S C Rastogi
Sep 13, 2002·Contact Dermatitis·Thomas BrinkmeierPeter J Frosch
Sep 13, 2002·Contact Dermatitis·Wolfgang UterUNKNOWN IVDK Study Group and the German Contact Dermatitis Research Group, DKG
Jun 10, 2004·Dermatologic Therapy·Denis Sasseville
Jul 28, 2004·Contact Dermatitis·Courtney Herbert, Robert L Rietschel
Nov 13, 2004·International Archives of Occupational and Environmental Health·Johannes GeierWolfgang Uter
Jun 29, 2005·Contact Dermatitis·Mari-Ann Flyvholm
Aug 23, 2005·Journal of the American Academy of Dermatology·David A WetterArnold L Schroeter
Sep 1, 2005·Contact Dermatitis·D P BruynzeelUNKNOWN European Environmental and Contact Dermatitis Research Group
Jan 24, 2006·Contact Dermatitis·Søren Vig LehmannBo Kreilgaard
Jun 28, 2006·Dermatitis : Contact, Atopic, Occupational, Drug·Robert L RietschelDonald V Belsito
Jan 25, 2007·Contact Dermatitis·Michal Freireich-AstmanAkiva Trattner
Jul 14, 2007·Contact Dermatitis·Berit Christina CarlsenJeanne Duus Johansen
Aug 8, 2007·Contact Dermatitis·Cherng T JongMahbub M U Chowdhury

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Citations

Mar 25, 2014·Actas dermo-sifiliográficas·P González-MuñozS Vañó-Galván
Feb 8, 2016·Actas dermo-sifiliográficas·V Zaragoza-NinetJ de la Cuadra-Oyanguren
Jun 29, 2013·Clinics in Dermatology·Ronni WolfVincenzo Ruocco
Jul 25, 2015·Toxicological Sciences : an Official Journal of the Society of Toxicology·Russel M WaltersLorena Telofski
Sep 29, 2011·Contact Dermatitis·Ana Rita TravassosAn Goossens
Jul 5, 2011·Contact Dermatitis·Karin LehnerWolfgang Bäumler
Nov 3, 2010·Contact Dermatitis·Jochen BraschUNKNOWN German Contact Dermatitis Group (DKG)
Feb 5, 2013·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Flora B de Waard-van der SpekArnold P Oranje
Jul 20, 2011·Contact Dermatitis·Nuria LatorreJuan Francisco Silvestre
Feb 22, 2011·The British Journal of Dermatology·A SchnuchW Uter
Oct 23, 2012·The Australasian Journal of Dermatology·Elizabeth T ChowRosemary Nixon
Jul 13, 2011·Contact Dermatitis·Sophie OsdoitGérard Guillet
Dec 9, 2010·Contact Dermatitis·Kerem YazarCarola Lidén
Mar 19, 2014·Contact Dermatitis·Ulrik Fischer FriisJeanne Duus Johansen
Dec 19, 2013·Contact Dermatitis·Wolfgang UterCarola Lidén
Sep 2, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·L HorevM Bruze
Jun 19, 2010·Contact Dermatitis·Anton C de Groot, Howard I Maibach
Feb 23, 2011·Actas dermo-sifiliográficas·N LatorreA F Monteagudo
Feb 24, 2015·International Journal of Cosmetic Science·C LvH Cheng
Oct 8, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·A DinklohA Wollenberg
May 3, 2014·SAR and QSAR in Environmental Research·G PatlewiczO Mekenyan
Sep 11, 2014·Dermatitis : Contact, Atopic, Occupational, Drug·Elizabeth YimAntonella Tosti
Mar 25, 2017·Dermatitis : Contact, Atopic, Occupational, Drug·Kelly A Aschenbeck, Erin M Warshaw
Oct 14, 2017·International Journal of Toxicology·Lillian C Becker
Mar 25, 2017·Dermatitis : Contact, Atopic, Occupational, Drug·Kelly A Aschenbeck, Erin M Warshaw
Oct 17, 2019·Contact Dermatitis·Tatiana Sanz-SánchezAna M Giménez Arnau
Jul 7, 2015·Open Medicine·Laura MalinauskieneMarléne Isaksson
Jul 1, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Noureddine HallaMaria Filomena Barreiro
Mar 16, 2017·Dermatitis : Contact, Atopic, Occupational, Drug·Andrew SchemanNineveh Youkhanis
Jun 2, 2018·Journal of Cosmetic Dermatology·Jane Snatchfold
Feb 13, 2021·Regulatory Toxicology and Pharmacology : RTP·Lucía López-SánchezVirginia Merino

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