PMID: 9654353Jul 8, 1998Paper

Formation and sequence analysis of secretoneurin, a neuropeptide derived from secretogranin II, in mammalian, bird, reptile, amphibian and fish brains

Neuroscience Letters
B LeitnerR Fischer-Colbrie

Abstract

Secretoneurin is a recently-characterized neuropeptide derived from secretogranin II, a protein belonging to the class of chromogranins. We investigated the phylogeny of this peptide by immunoblotting and gel-filtration high performance liquid chromatography followed by radioimmunoassay of brain extracts of various species including chicken, lizard, frog and fish. In addition the amino acid sequence of secretoneurin from pig, hamster, rabbit, guinea-pig and chicken was established by reverse transcriptase polymerase chain reaction. Secretoneurin is strongly conserved during evolution, it is not only expressed in various mammalian species but found also in the brain of birds, reptiles, amphibians and fish. In all these species a significant or near complete processing of secretogranin II to secretoneurin was observed. These data provide significant evidence for the neuropeptide nature of the novel functional peptide.

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Citations

Jan 12, 2002·Regulatory Peptides·Gudrun WakoniggAlois Saria
Nov 17, 2007·Acta Physiologica·M Montero-HadjadjeY Anouar
Aug 25, 2011·Endocrine Reviews·Alessandro BartolomucciStephen R J Salton
Jun 16, 2009·General and Comparative Endocrinology·E ZhaoVance L Trudeau
Jun 9, 2010·Journal of Anatomy·Doris AllerstorferMichael J F Blumer
Dec 27, 2005·General and Comparative Endocrinology·E ZhaoVance L Trudeau
Dec 2, 2014·General and Comparative Endocrinology·Carlos G Martinez-MorenoSteve Harvey
Jun 30, 2006·Neuropeptides·E ZhaoVance L Trudeau
Nov 21, 2018·Critical Reviews in Clinical Laboratory Sciences·Magnus Nakrem LyngbakkenTorbjørn Omland
Feb 8, 2011·American Journal of Physiology. Heart and Circulatory Physiology·Calvin K Y Chan, Paul M Vanhoutte

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