Formation of Alkanethiol Supported Hybrid Membranes Revisited

Biotechnology Journal
Zelun ZhiAdam Mechler

Abstract

A phospholipid monolayer supported on an alkanethiol self-assembled monolayer (SAM) constitutes a supported hybrid membrane, a model of biological membranes optimized for electronic access through the underlying metal support surface. It is believed that phospholipids, when deposited from aqueous liposome suspension, spontaneously cover the alkanethiol-modified surface, owing to the reduction of surface free energy of the hydrophobic alkane surface exposed to the solution. However, the formation of the hybrid layer has to overcome significant energy barriers in rupturing the vesicle and "unzipping" the membrane leaflets; hence drivers of the spontaneous hybrid membrane formation are unclear. In this work, the authors studied the efficiency of the liposome deposition method to form hybrid membranes on octanethiol and hexadecanethiol SAMs in aqueous environment. Using quartz crystal microbalance to monitor the deposition process it was found that the hybrid membrane did not form spontaneously; the deposit was dominated by hemi-fused liposomes that can only be removed by applying osmotic stress. However, osmotic stress yielded a reproducible layer characterized by ≈-5Hz frequency change that is also confirmed by fluorescence micro...Continue Reading

References

Apr 21, 1975·Biochimica Et Biophysica Acta·J N Israelachvili, D J Mitchell
May 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·C Tanford
Feb 1, 1993·Biophysical Journal·B L MuiT D Madden
Sep 16, 2000·Physical Review Letters·C A KellerB Kasemo
Nov 7, 2000·Biochimica Et Biophysica Acta·J F Nagle, S Tristram-Nagle
Dec 18, 2001·Biosensors & Bioelectronics·Víctor H Pérez-LunaGabriel P López
Jun 20, 1996·Chemical Reviews·Abraham Ulman
Nov 26, 2002·Chemistry & Biology·Andrey S KlymchenkoAlexander P Demchenko
Dec 6, 2002·Journal of the American Chemical Society·Vitalii I SilinAnne L Plant
Mar 1, 2003·Biophysical Journal·Jared C LawrenceRobert M Henderson
Oct 29, 2003·Biophysical Journal·Ralf RichterAlain Brisson
Sep 21, 2004·Biophysical Journal·M M A E ClaessensM A Cohen Stuart
Apr 14, 2005·Chemical Reviews·J Christopher LoveGeorge M Whitesides
Jul 18, 2006·Biophysical Journal·J BorejdoI Gryczynski
May 29, 2007·The Journal of Physical Chemistry. B·M M A E ClaessensM A Cohen Stuart
Jul 31, 2007·Journal of the American Chemical Society·Nam-Joon ChoCurtis W Frank
Nov 18, 2008·Biochimica Et Biophysica Acta·Lanlan YuThorsten Wohland
May 2, 2009·Journal of Colloid and Interface Science·John T Woodward, Curtis W Meuse
Oct 7, 2010·Small·Marta BallyBrigitte Städler
Apr 14, 2011·Biomedical Microdevices·Bala Murali VenkatesanRashid Bashir
Sep 8, 2011·Proceedings of the National Academy of Sciences of the United States of America·Stephen H DonaldsonJacob N Israelachvili
Sep 1, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Matthew K Strulson, Joshua A Maurer
Jan 15, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Nicole HainIlya Reviakine
Aug 2, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Joshua A JackmanNam-Joon Cho
Mar 19, 2014·The Journal of Physical Chemistry. B·Goh Haw ZanNam-Joon Cho
Aug 12, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Seyed R TabaeiNam-Joon Cho
Dec 17, 2014·ACS Applied Materials & Interfaces·Joshua A JackmanNam-Joon Cho
Feb 14, 2015·Langmuir : the ACS Journal of Surfaces and Colloids·Seyed R TabaeiNam-Joon Cho
Apr 11, 2015·Physical Chemistry Chemical Physics : PCCP·Seyed R TabaeiNam-Joon Cho
Apr 29, 2015·Langmuir : the ACS Journal of Surfaces and Colloids·Soichiro MatsunagaMaki Kawai
Jun 16, 2015·Soft Matter·Imad Younus Hasan, Adam Mechler
Apr 20, 2016·ACS Applied Materials & Interfaces·Seyed R TabaeiNam-Joon Cho
Sep 16, 2016·Journal of Colloid and Interface Science·Zahra BesharatMark W Rutland
Oct 21, 2016·Accounts of Chemical Research·Mingming Wang, Wei Zhan
Oct 27, 2016·Biointerphases·Imad Younus Hasan, Adam Mechler
Feb 25, 2017·Journal of the American Chemical Society·Galina V DubachevaRalf P Richter
Apr 11, 2017·Biochimica Et Biophysica Acta. Biomembranes·Zhenfu ZhangClaudiu Gradinaru
Aug 2, 2017·The Analyst·Imad Younus Hasan, Adam Mechler

❮ Previous
Next ❯

Citations

Dec 12, 2018·Biotechnology Journal·William E BentleyTakeshi Gotoh

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Langmuir : the ACS Journal of Surfaces and Colloids
Eftim MilkaniW Grant McGimpsey
Langmuir : the ACS Journal of Surfaces and Colloids
Rory StineCara-Lynne Schengrund
Journal of the American Chemical Society
Neil A AndersonKimberly A Briggman
© 2022 Meta ULC. All rights reserved