PMID: 4909469Apr 1, 1970Paper

Formation of all stable RNA species in Escherichia coli by posttranscriptional modification

Proceedings of the National Academy of Sciences of the United States of America
B PaceN R Pace

Abstract

The kinetics of accumulation of the known stable RNA species (23S, 16S, and 5S rRNA and tRNA) in Escherichia coli C122 were monitored by polyacrylamide gel electrophoresis of purified cellular RNA, following termination of brief pulse labeling with (32)P-orthophosphate. Isotopically labeled stable RNA species appear only after a time lag, while total cellular RNA and the ostensible precursors to the stable RNA classes accumulate from the earliest times examined. It is concluded that all the known stable RNA species in E. coli are the products of posttranscriptional modification.

References

Dec 14, 1969·Journal of Molecular Biology·M Adesnik, C Levinthal
Jun 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·G AttardiS Kabat
Apr 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·N B HechtC R Woese
Jun 1, 1969·Proceedings of the National Academy of Sciences of the United States of America·M Bleyman, C Woese
Jul 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·D R MillsS Spiegelman
Aug 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·N R PaceS Spiegelman
Jun 8, 1965·Biochimica Et Biophysica Acta·R Lindigkeit, W Handschack
Jun 28, 1967·Journal of Molecular Biology·D H BishopS Spiegelman

❮ Previous
Next ❯

Citations

Jan 1, 1972·Molecular & General Genetics : MGG·H W SchaupC Woese
Dec 1, 1973·Molecular Biology Reports·T J Stoof, R J Planta
Jun 1, 1977·Developmental Biology·J A Lengyel, S Penman
Apr 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·M J Duncan, L Gorini
Sep 14, 1971·Journal of Molecular Biology·G CorteP Venkov
Mar 14, 1971·Journal of Molecular Biology·A Yuki
Oct 14, 1972·Journal of Molecular Biology·J FeunteunR Monier
Aug 25, 1974·Journal of Molecular Biology·A H Dougan, D A Glaser
Apr 25, 1973·Journal of Molecular Biology·N R PaceC W Radcliffe
Jun 12, 2014·Frontiers in Genetics·Jamie A AbbottSusan M Robey-Bond
Oct 17, 1970·Nature·D E PettijohnC R Kossman
Oct 17, 1977·European Journal of Biochemistry·K Fink, G Turnock
Nov 24, 1971·Nature: New Biology·C R KossmanD E Pettijohn
Feb 3, 1971·Nature: New Biology·P M Lizardi, D J Luck
Jul 14, 1971·Nature: New Biology·M SoginC R Woese
Oct 24, 2007·The Journal of Nutrition·Robert R WolfeXiao-jun Zhang
Aug 1, 1971·Journal of Bacteriology·R L PetersonN R Pace
Feb 1, 1974·Journal of Bacteriology·P R DobsonM L Sogin
Dec 1, 1981·Microbiological Reviews·P Gegenheimer, D Apirion

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.