Formation of contact active antimicrobial surfaces by covalent grafting of quaternary ammonium compounds

Colloids and Surfaces. B, Biointerfaces
Poverenov Elena, Klein Miri

Abstract

Different synthetic strategies for the formation of contact active antimicrobial materials utilizing covalent linkage of quaternary ammonium compounds (QACs) were reviewed. There is a demand to find methods that will prevent bacterial fouling without the release of antimicrobial agents, because biocides cause environment pollution and promote the development of bacteria resistance mechanisms. The contact active antimicrobial surfaces may provide a useful tool for this purpose. The covalent surface grafting of QACs seems to be a feasible and promising approach for the formation of safe and effective antimicrobial materials that could be utilized for medical devices, food industry, water treatment systems and other applications. This manuscript reviews covalent attachment of QACs to form contact active antimicrobial materials based on glass, metals, synthetic and natural polymers. The review emphasizes the description of different synthetic methods that are used for the covalent linkage. Direct covalent linkage of QACs to the material surfaces, a linkage via auxiliary nanoparticles (NPs), or spacers, controlled radical polymerization techniques and a linkage to pre-activated surfaces are discussed. The physico-chemical properties...Continue Reading

Citations

Feb 5, 2019·Journal of Food Science·Joshua E HerskovitzJulie M Goddard
Jul 4, 2019·Macromolecular Bioscience·Adolfo Del CampoAlexandra Muñoz-Bonilla
May 13, 2020·Journal of Functional Biomaterials·Aleksandra MiletićBranka Pilić
May 15, 2021·International Journal of Biological Macromolecules·Balasubramanian RukmanikrishnanJaewoong Lee
Jul 3, 2021·Nanomaterials·Francisco G BlancoM Auxiliadora Prieto
Aug 22, 2020·Journal of Agricultural and Food Chemistry·Yongfei HuangLi Li
Aug 17, 2021·Journal of Materials Science·Urbashi MahantaAtul Suresh Deshpande
Nov 24, 2020·Biomacromolecules·Shuyue ZhaoAnjie Dong
Oct 13, 2021·ACS Biomaterials Science & Engineering·Yunyi BoYingna He

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