Formation of Fluorohydroxyapatite with Silver Diamine Fluoride

Journal of Dental Research
May Lei MeiC H Chu

Abstract

Silver diamine fluoride (SDF) is found to promote remineralization and harden the carious lesion. Hydroxyapatite crystallization is a crucial process in remineralization; however, the role of SDF in crystal formation is unknown. We designed an in vitro experiment with calcium phosphate with different SDF concentrations (0.38, 1.52, 2.66, 3.80 mg/mL) to investigate the effect of this additive on the nucleation and growth of apatite crystals. Two control groups were also prepared-calcium phosphate (CaCl2·2H2O + K2HPO4in buffer solution) and SDF (Ag[NH3]2F in buffer solution). After incubation at 37oC for 24 h, the shape and organization of the crystals were examined by bright-field transmission electron microscopy and electron diffraction. Unit cell parameters of the obtained crystals were determined with powder X-ray diffraction. The vibrational and rotational modes of phosphate groups were analyzed with Raman microscopy. The transmission electron microscopy and selected-area electron diffraction confirmed that all solids precipitated within the SDF groups were crystalline and that there was a positive correlation between the increased percentage of crystal size and the concentration of SDF. The powder X-ray diffraction patterns...Continue Reading

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Citations

Jan 23, 2018·Advances in Dental Research·J O Burgess, P M Vaghela
Feb 2, 2018·Healthcare·Kitty Jieyi ChenChun Hung Chu
Oct 7, 2018·Oral Diseases·Xiuqing WangLinglin Zhang
Jan 15, 2020·Dental Materials Journal·Aye Ko KoJunji Tagami
Feb 14, 2020·Operative Dentistry·L F Espíndola-CastroGqm Monteiro
Jun 12, 2020·Regenerative Biomaterials·Longjiang DingLinglin Zhang
May 18, 2018·Journal of Dental Research·M L MeiC H Chu
Jan 28, 2021·European Journal of Oral Sciences·Maria Jacinta Rosario H Romero, Frank Lippert
Feb 23, 2021·The Journal of International Medical Research·Jing-Yuan PengKam-Jung Low
Mar 9, 2021·Restorative Dentistry & Endodontics·Jaqueline Costa FavaroSandrine Bittencourt Berger
May 23, 2020·International Journal of Clinical Pediatric Dentistry·Venugopal R NagireddyAnnie Chris
Nov 30, 2018·Dental Materials : Official Publication of the Academy of Dental Materials·Ollie Yiru YuChun-Hung Chu
Jan 1, 2020·Journal of Dentistry·May Lei MeiChun Hung Chu
Aug 16, 2021·Journal of Dentistry·Chloe Meng JiangChun Hung Chu
Sep 21, 2020·Journal of Dentistry·May Lei MeiChun Hung Chu

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Methods Mentioned

BETA
transmission
X-ray
Scanning Electron Microscopy
electron diffraction

Software Mentioned

SPSS
ImageJ

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