PMID: 16538030Mar 16, 2006Paper

Formation of follicular cysts in cattle and therapeutic effects of controlled internal drug release

The Journal of Reproduction and Development
Junichi Todoroki, Hiroyuki Kaneko

Abstract

Follicular cysts in cattle result from excessive growth of the dominant follicle without ovulation and still constitute a major reproductive disorder in this species. One key hormonal characteristic of cows with follicular cysts is the lack of an LH surge, although they have increased plasma estradiol concentrations. Another is a relatively high level of pulsatile secretion of LH that promotes continued growth of the dominant follicle. These LH characteristics seem to result from a functional abnormality in the feedback regulation of LH secretion by estradiol. Treatment with controlled internal drug release devices that increase circulating progesterone levels is effective in resolving follicular cystic conditions by 1) lowering pulsatile LH secretion and 2) restoring the ability of the hypothalamo-pituitary axis to generate an LH surge in response to an increase in circulating estradiol.

References

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May 1, 1984·The British Veterinary Journal·E D Watson, C D Munro
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Jul 1, 2004·The Journal of Reproduction and Development·Junichi TodorokiHiroyuki Kaneko
Aug 1, 1979·Theriogenology·D J KeslerC J Bierschwal

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Citations

Nov 26, 2008·Reproduction : the Official Journal of the Society for the Study of Fertility·M A VelazquezH Niemann
May 15, 2010·Research in Veterinary Science·Abd el-Gawad Salah el-Tahawy, Mostafa Mohammed Fahmy
Sep 3, 2011·Reproduction in Domestic Animals = Zuchthygiene·A DehghanS Momeni Bigdeli
Apr 13, 2015·Tropical Animal Health and Production·Chainarong NavanukrawSuneerat Aiumlamai
Jan 28, 2020·The Journal of Reproduction and Development·Rebecca LappAndreas Vernunft

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