PMID: 7019677Nov 1, 1980Paper

Formation of mutagens by sorbic acid-nitrite reaction: effects of reaction conditions on biological activities

Mutation Research
M NamikiT Kada

Abstract

Conditions of the reaction between sorbic acid and sodium nitrite generating mutagenic principles were examined. In the rec-assay and the Ames reversion assay, the maximal mutagenic activity was obtained in a pH range of 3.5-4.2. Mutagenic and growth-inhibitor activities of five C-nitro and C-nitroso compounds were studied. The product Y, 2-methyl-1,4-dinitropyrrole, was the strongest mutagen among them.

References

Jan 1, 1975·Journal of the Science of Food and Agriculture·D S MottramT A Gough
Dec 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J McCannB N Ames

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Citations

Jul 1, 1981·Mutation Research·T OsawaK Namiki
Jan 1, 1992·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·R JungE Lück
Aug 30, 2000·Toxicology in Vitro : an International Journal Published in Association with BIBRA·C FerrandG de Saint Blanquat
Mar 29, 2001·Food Additives and Contaminants·C FerrandG de Saint Blanquat
Jan 27, 2017·Annual Review of Food Science and Technology·Marilyn C Erickson, Michael P Doyle
Sep 1, 1987·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·T Kada, K Shimoi
Mar 1, 2019·EFSA Journal·UNKNOWN EFSA Panel on Food Additives and Flavourings (FAF)Ine Waalkens-Berendsen
Nov 16, 2019·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Luciano MolognoniJuliano De Dea Lindner
Jul 8, 2009·Chemical Research in Toxicology·M Teresa Pérez-PriorJulio Casado
Feb 4, 2010·The Journal of Organic Chemistry·M Teresa Pérez-PriorJulio Casado
Aug 28, 2020·Food Research International·Gabriel Emiliano MottaJuliano De Dea Lindner
Aug 24, 2000·Journal of Agricultural and Food Chemistry·C FerrandG de Saint Blanquat

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