PMID: 6402383Feb 21, 1983Paper

Formation of the COOH-terminal amide group of thyrotropin-releasing-factor

FEBS Letters
I Husain, S S Tate

Abstract

The precursors of peptide hormones that possess a COOH-terminal alpha-amide group contain a glycine residue following the amino acid which is amidated in the hormone. Less than Glu-His-Pro-Gly was synthesized as a putative precursor of thyroliberin. Bovine pituitary neurosecretory granules were shown to contain an amide group-forming activity associated with an Mr of about 62 000 protein(s) which converts the tetrapeptide to thyroliberin.

References

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Citations

Aug 10, 2000·Medicinal Research Reviews·L ProkaiN Bodor
Jan 1, 1989·Neurochemistry International·C LoudesA Faivre-Bauman
Jul 6, 2000·Bioorganic & Medicinal Chemistry·S H YoonN Bodor
May 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·J S KizerW W Youngblood
Jan 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·L OuafikC Oliver
Jun 1, 1990·International Journal of Andrology·A E PekaryS Friedman
Aug 17, 1987·European Journal of Biochemistry·A Bleakman, D G Smyth
Jan 1, 1989·Annals of the New York Academy of Sciences·I M Jackson
Oct 1, 1983·Neuropeptides·M C Beinfeld
Jan 1, 1987·Annals of the New York Academy of Sciences·Y P Loh
May 1, 1988·Journal of Neurochemistry·F Meng, K Tsou
Aug 7, 2002·The Journal of Pharmacy and Pharmacology·Jiaxiang WuNicholas Bodor
Dec 1, 1987·Bioscience Reports·A F Bradbury, D G Smyth
Apr 1, 1985·Nutrition Reviews
Nov 1, 1985·Metabolism: Clinical and Experimental·G S WandR E Mains
Feb 15, 1988·Archives of Biochemistry and Biophysics·N M MehtaR S Birnbaum
Mar 1, 1990·Analytical Biochemistry·A Y JengJ P Gilligan
Jul 16, 1986·Biochemical and Biophysical Research Communications·L OuafikC Oliver
Jun 30, 1986·Biochemical and Biophysical Research Communications·K MizunoH Matsuo
Oct 15, 1986·Biochemical and Biophysical Research Communications·J SakataH Matsuo
Dec 2, 1999·Journal of Medicinal Chemistry·L ProkaiN Bodor

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