PMID: 8361493Jul 1, 1993

Formation of various types of complexes upon the interaction of anthraquinones with DNA

Molekuliarnaia biologiia
V I SalianovIu M Evdokimov

Abstract

The optical properties (circular and linear dichroism) of the 11 anthraquinone antibiotics complexed with DNA molecules under conditions giving rise to cholesteric liquid-crystalline dispersions were investigated. Complexes of compounds A911 and A912 with double-stranded linear or circular DNA molecules differ strongly in their properties from those of other anthraquinones. The possible reasons of these differences and their possible correlation with the biological activity of the A911 and A912 are discussed.

Related Concepts

Antibiotic throat preparations
Anthraquinone dye
Complex (molecular entity)
Antifungal Antibiotics, Topical
9,10-anthraquinone
Anthraquinones
Antibiotics, Gynecological
Salmo salmo
Crystal Structure
Circular Dichroism, Vibrational

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