Formula for calculating standard liver volume in Indians.

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
Anuradha ChandramohanSitaram Venkatramani

Abstract

To assess the validity of standard liver volume (SLV) calculated using various formulae in the Indian population. Data on liver weights of 366 cadavers with no intrinsic liver disease were obtained retrospectively from autopsy records. From these, liver volume (LV) was calculated using the density of formalin-preserved livers, measured prospectively in 15 livers. These volumes were compared with SLV estimated using various formulae. The liver density was found to be 1.162 kg/L. Median (range) age of 366 autopsied cadavers (M:F = 274:92) was 49 [18-70] years. Median (range) body surface area (BSA) and LV was 1.66 (1.25-2.12) square meter and 1,205 (685.3-2102) cc, respectively. There was poor agreement between LV obtained from autopsy data and SLV estimated using formulae derived from the Indians (Indian Model 1: ICC = -0.069, p = 0.655; Indian Model 2: ICC = -0.07015, p = 0.879; Indian Model 3: ICC = -0.06253, p = 0.043), Koreans (ICC = -0.07114, p = <0.0001), Chinese (ICC = -0.0286, p = <0.0001) and Johnson Model (ICC = -0.05764, p = <0.0001). Median difference between the actual LV and SLV as estimated by the Indian Models 1 and 2 are least (29 cc and 6 cc, respectively) and this was followed by Johnson and the Korean Models ...Continue Reading

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Citations

May 3, 2014·Metallomics : Integrated Biometal Science·Carlos Angelé-MartínezJulia Brumaghim

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