Formulation and Characterization of Potential Antifungal Oleogel with Essential Oil of Thyme

Evidence-based Complementary and Alternative Medicine : ECAM
Giedre KasparavicieneJurga Bernatoniene

Abstract

The aim of this research was to formulate oleogel with thyme essential oil with potential antimicrobial activity, design optimal formulation, and evaluate the influence of ingredients on texture parameters of preparation. Central composite design was applied to statistical optimization of colloidal silica and paraffin oil mixture for the modeling of oleogel delivery system. The influence of designed formulations on response variables (texture parameters), firmness, cohesiveness, consistency, and index of viscosity, was evaluated. Quality of essential oil of thyme was assessed by determinate concentration of thymol and carvacrol using gas chromatography with flame ionization detection (GC-FID). Microbiological tests have shown that oleogel with thyme essential oil affects Candida albicans microorganism when thyme essential oil's concentration is 0,05% in oleogel mixture.

References

Dec 18, 2003·Journal of the European Academy of Dermatology and Venereology : JEADV·C Pina-VazJ Martinez-de-Oliveira
May 8, 2009·Forschende Komplementärmedizin = Research in Complementary Medicine·Jürgen ReichlingReinhard Saller
Sep 29, 2011·Annual Review of Entomology·Catherine Regnault-RogerJohn Thor Arnason
Jan 31, 2012·Maturitas·Myeong Soo LeeEdzard Ernst
May 27, 2015·International Journal of Cosmetic Science·C RichardY Mofid
Dec 21, 2016·Evidence-based Complementary and Alternative Medicine : ECAM·Giedre KasparavicieneJurga Bernatoniene
Mar 28, 2017·Burns : Journal of the International Society for Burn Injuries·Monika SienkiewiczHanna Zielińska-Bliźniewska
May 27, 2017·Evidence-based Complementary and Alternative Medicine : ECAM·Ané Orchard, Sandy van Vuuren

❮ Previous
Next ❯

Citations

Jun 19, 2021·Frontiers in Pharmacology·Dereje NigussieEyasu Makonnen

❮ Previous
Next ❯

Software Mentioned

Expert
Stat
Aerosil
- Expert®
Design

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Related Papers

Journal of the American Pharmaceutical Association
E E LANGENAU
Journal of the American Pharmaceutical Association
L FIBRANZC E MILLER
Wei sheng wu xue bao = Acta microbiologica Sinica
M Fan, J Chen
© 2022 Meta ULC. All rights reserved