Formulation and Validation of a Functional Assay-Driven Model of Nanoparticle Aquatic Transport

Environmental Science & Technology
Nicholas K GeitnerMark R Wiesner

Abstract

Here, we present a model for the prediction of nanoparticle fate in aquatic environments, parametrized using functional assays that take into account conditions of the environmental media and nanoparticle properties. The model was used to explore scenarios for five nanomaterials in a freshwater wetland setting and compared with experimental results obtained in mesocosm studies. Material characteristics used in the model were size, density, dissolution rate constants, and surface attachment efficiencies. Model predictions and experimentally measured removal rate constants from the water column were strongly correlated, with Pearson correlation coefficient 0.993. Further, the model predicted removal rate constants quantitively very close to measured rates. Of particular importance for accurate predictions were two key processes beyond the usual heteroaggregation with suspended solids. These were homoaggregation of nanomaterials and nanomaterial attachment to aquatic plant surfaces. These results highlight the importance of including all relevant aggregation and deposition processes over short time scales for nanoparticle transport, while demonstrating the utility of functional assays for surface attachment as model inputs.

References

Feb 3, 2011·Journal of Environmental Quality·Ernest M HotzeGregory V Lowry
Apr 17, 2012·Environmental Science & Technology·Antonia PraetoriusKonrad Hungerbühler
Jul 18, 2012·Environmental Science & Technology·Lei WuYakov A Pachepsky
Nov 5, 2013·Environmental Science & Technology·Clement LevardGregory V Lowry
Feb 20, 2014·Environmental Science & Technology·Haoyang Haven Liu, Yoram Cohen
Apr 15, 2014·The Science of the Total Environment·Mathieu TherezienMark R Wiesner
Jan 23, 2015·Environmental Science & Technology·Amy L DaleMohammed Baalousha
Jul 21, 2015·The Science of the Total Environment·Christine Ogilvie HendrenMark R Wiesner
Jun 2, 2016·Environmental Science & Technology·Nicholas K GeitnerMark R Wiesner
Oct 17, 2016·Environmental Pollution·Ellen BesselingAlbert A Koelmans
Jul 8, 2017·Environmental Science & Technology·Nicholas K GeitnerMark R Wiesner
Oct 19, 2017·Environmental Science & Technology·Nicholas K GeitnerMark R Wiesner
Dec 22, 2017·Environmental Science & Technology·Olubukola S AlimiNathalie Tufenkji
Mar 6, 2018·Environmental Science & Technology·Benjamin P EspinasseMark R Wiesner
Aug 2, 2018·Environmental Science & Technology·Nicholas K GeitnerHeileen Hsu-Kim
Aug 15, 2018·Nature Nanotechnology·Astrid AvellanGregory V Lowry

❮ Previous
Next ❯

Citations

Jul 2, 2020·International Journal of Molecular Sciences·Edward SuhendraYi-Chin Hsieh
Apr 27, 2021·Environmental Science. Processes & Impacts·Hannah M McMillanChristine Ogilvie Hendren

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.