Fortifying the link between SIRT1, resveratrol, and mitochondrial function.

Cell Metabolism
John M Denu

Abstract

The molecular mechanisms behind the health benefits of resveratrol remain enigmatic and controversial. In this issue of Cell Metabolism, Price et al. establish a clear chemical-genetic connection between SIRT1 and resveratrol, providing strong evidence that SIRT1 is critical for resveratrol to stimulate mitochondrial biogenesis and a switch toward oxidative muscle fibers (Price et al., 2012).

Citations

Dec 18, 2013·Journal of Physiology and Biochemistry·Roger A VaughanCarole A Conn
Jun 8, 2014·Journal of Pharmaceutical and Biomedical Analysis·Mario Thevis, Wilhelm Schänzer
Dec 24, 2014·Journal of Cellular Biochemistry·Angelika Dampf StonePeter W Jurutka
Dec 27, 2015·Nutrition·Gustavo Tomas Diaz-GereviniAldo Renato Eynard
Oct 30, 2012·Free Radical Biology & Medicine·Brian J Morris
Oct 11, 2015·Journal of Physiology and Biochemistry·Xihong ZhouWu Xin
Jul 28, 2015·Mass Spectrometry Reviews·Wilhelm Schänzer, Mario Thevis
Dec 8, 2015·Oxidative Medicine and Cellular Longevity·Erik A FraunbergerAna C Andreazza
Sep 18, 2015·Physiological Reviews·Elizabeth W BradleyJennifer J Westendorf
May 14, 2020·Nutrients·Assylzhan YessenkyzyTalgat Nurgozhin

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