PMID: 15233313Jul 6, 2004Paper

Forty-year mortality from cardiovascular diseases and all causes of death in the US Railroad cohort of the Seven Countries Study

European Journal of Epidemiology
Alessandro MenottiM Lanti

Abstract

Forty-year mortality and its association with entry risk factor levels is reported in men employed in the US Railroad industry within the Seven Countries Study of Cardiovascular Diseases. Cardiovascular risk factors were measured in 2571 men aged 40-59 at entry examination in 1957-1959 and after 5 years. Mortality data were collected during 40 years of follow-up (overall mortality of 83.4%). The main causes of death were coronary heart disease (CHD, 32.9% of all causes using strict criteria), atherosclerotic cardiovascular diseases (including coronary, stroke and peripheral artery diseases, (ACVD), 53.2% of all causes) and cancer (25.1% of all causes). Multivariate analysis showed that age, systolic blood pressure, serum cholesterol and cigarette consumption were strongly and significantly associated with all-cause mortality, coronary mortality and cardiovascular mortality. Multivariate relative risks per 5 years of age were 1.31 for all-causes, 1.32 for CHD and 1.36 for ACVD; per 20 mmHg systolic blood pressure were 1.12, 1.23 and 1.26, respectively; per 1 mmol/l of serum cholesterol were 1.06, 1.18 and 1.14, respectively; and per 10 cigarettes smoked per day were 1.14, 1.12 and 1.13, respectively. During a 40-year period clas...Continue Reading

Citations

Sep 29, 2006·International Urology and Nephrology·Konstantinos N StamatiouFragiskos Sofras
Nov 11, 2009·Expert Review of Cardiovascular Therapy·Vivencio Barrios, Carlos Escobar
Jun 13, 2006·American Journal of Industrial Medicine·Eric GarshickBernard Rosner
Mar 9, 2011·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Ingar Holme, Serena Tonstad
Nov 15, 2011·European Journal of Preventive Cardiology·David FaehMatthias Bopp
Feb 12, 2013·European Journal of Epidemiology·Carolin GellertHermann Brenner
Jun 30, 2011·European Journal of Epidemiology·Paolo Emilio PudduAnthony George Kafatos
Jul 30, 2011·The Urologic Clinics of North America·Keith R Solomon, Michael R Freeman

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