Foscarnet and Ganciclovir in the treatment of CMV retinitis in AIDS patients: a randomised comparison.

The Journal of Infection
G MoyleB G Gazzard

Abstract

Ganciclovir and Foscarnet were compared in an open randomised trial as treatment and secondary prophylaxis of cytomegalovirus (CMV) retinitis in patients with AIDS. Patients responded more rapidly to Ganciclovir than to Foscarnet although eventual response rates were similar with both drugs. During maintenance therapy there were trends towards more delayed reactivation of CMV and fewer adverse events requiring changes in therapy, in the Ganciclovir group. However, these patients had more line infections and a higher blood transfusion requirement.

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Citations

Feb 16, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·William A PearceHoward F Fine
Jul 26, 2019·Neurology. Clinical Practice·Elizabeth FortinSashank Prasad
Aug 1, 1996·The British Journal of Ophthalmology·C W YungS Wolf

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