fost12, the Fusarium oxysporum homolog of the transcription factor Ste12, is upregulated during plant infection and required for virulence

Fungal Genetics and Biology : FG & B
M Asunción García-SánchezJosé María Díaz-Mínguez

Abstract

We have identified a Fusarium oxysporum homolog of the Ste12 transcription factor that regulates mating and filamentation in Saccharomyces cerevisiae. The corresponding gene, fost12, from a highly virulent strain of F. oxysporum f. sp. phaseoli, was confirmed to share a high level of similarity and possessed the STE and C2H2 domains characteristic of the fungal Ste12 transcription factor family of proteins. Disruption of fost12 resulted in no visible alterations of colony morphology or in vitro growth characteristics. However, the disruption mutants showed a substantial reduction in virulence when inoculated in common bean seedlings. In planta transcription of fost12 is drastically increased between 12 and 24h after inoculation, as detected by real-time RT-PCR. The results of the transcriptional analyses carried out in several F. oxysporum strains during axenic growth suggest that the fost12 gene product is a virulence factor required to deal with the nutritional stress confronted by the pathogen during host plant colonization.

References

May 15, 1987·Analytical Biochemistry·J LogemannL Willmitzer
May 10, 1994·Molecular & General Genetics : MGG·G F Van den AckervekenP J De Wit
Mar 1, 1996·Current Biology : CB·W ChiuJ Sheen
Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Sep 23, 1997·Cell·H J LoG R Fink
Dec 9, 1997·Molecular Plant-microbe Interactions : MPMI·M ColemanR P Oliver
Jul 31, 1999·Applied and Environmental Microbiology·F M Alves-SantosJ M Díaz-Mínguez
Mar 8, 2000·The Journal of Experimental Medicine·Y C ChangK J Kwon-Chung
Jul 29, 2000·FEMS Microbiology Letters·C Csank, K Haynes
Mar 15, 2001·Proceedings of the National Academy of Sciences of the United States of America·Y C ChangK J Kwon-Chung
Sep 5, 2002·Microbiology and Molecular Biology Reviews : MMBR·Miguel A Peñalva, Herbert N Arst
Apr 16, 2003·Molecular Microbiology·Zaira CaracuelAntonio Di Pietro
May 15, 2003·Molecular Plant-microbe Interactions : MPMI·Gento TsujiYasuyuki Kubo
Jul 8, 2003·Current Genetics·Manuel D Ospina-GiraldoSeogchan Kang
Nov 7, 2006·FEMS Microbiology Letters·Hege H Divon, Robert Fluhr
Apr 28, 2007·Fungal Genetics and Biology : FG & B·Brisa RamosJosé María Díaz-Mínguez
Aug 24, 2007·Eukaryotic Cell·Xinhua ZhaoJin-Rong Xu
Aug 29, 2007·Molecular Plant-microbe Interactions : MPMI·Fernando Calero-NietoConcepcion Hera
Oct 24, 2008·Phytopathology·Fernando M Alves-SantosJosé María Díaz-Mínguez
Jun 16, 2009·Molecular Plant-microbe Interactions : MPMI·Nicolas Rispail, Antonio Di Pietro
Sep 1, 2003·Molecular Plant Pathology·Antonio Di PietroM Isabel G Roncero

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Citations

May 17, 2014·Molecular Plant Pathology·Qin GuZhonghua Ma
Oct 2, 2014·Molecular Plant-microbe Interactions : MPMI·Carmen Ruiz-RoldánM Isabel G Roncero
Aug 2, 2016·International Journal of Food Microbiology·Laura VilanovaPaloma Sánchez-Torres
Jan 29, 2016·Molecular Plant Pathology·Jonathan Niño-SánchezJosé María Díaz Mínguez
Aug 28, 2010·Communicative & Integrative Biology·Nicolas Rispail, Antonio Di Pietro
May 11, 2021·Molecular Plant Pathology·Qussai ZuriegatYingzi Yun

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