Four-Analog Computation Based on DNA Strand Displacement

ACS Omega
Chengye ZouYuan Liu

Abstract

DNA strand displacement plays an important role in biological computations. The inherent advantages of parallelism, high storability, and cascading have resulted in increased functional circuit realization of DNA strand displacement on the nanoscale. Herein, we propose an analog computation with minus based on DNA strand displacement. The addition, subtraction, multiplication, and division gates as elementary gates could realize analog computation with minus. The advantages of this proposal are the analog computation with negative value and division computation. In this article, we provide the designs and principles of these elementary gates and demonstrate gate performance by simulation. Furthermore, to show the cascade property of gates, we computed a polynomial as an example by these gates.

References

Sep 23, 1998·Neural Computation·R Sarpeshkar
Apr 30, 2004·Nature·Yaakov BenensonEhud Shapiro
Jul 22, 2011·Nature·Lulu QianJehoshua Bruck
Aug 10, 2011·IET Systems Biology·K Oishi, E Klavins
Jul 26, 2014·ACS Synthetic Biology·Boyan YordanovAndrew Phillips
Nov 5, 2014·PloS One·Wei DengHaojun Liang
Jan 13, 2015·Analytical and Bioanalytical Chemistry·Maria Chiara GiuffridaGiuseppe Spoto
Feb 7, 2015·Science·W Benjamin Rogers, Vinothan N Manoharan
Apr 26, 2016·ACS Synthetic Biology·Matthew R Lakin, Darko Stefanovic
May 11, 2016·IEEE Transactions on Nanobioscience·Rucha SawlekarDeclan G Bates
Jul 2, 2016·ACS Synthetic Biology·Tianqi SongJohn Reif
Oct 18, 2016·ACS Synthetic Biology·Joshua FernRebecca Schulman

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Software Mentioned

Visual GEC
MATLAB

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