Four cases of coronavirus disease 2019 in the early stage of pandemic of South Korea: a single public hospital experience

The Korean Journal of Internal Medicine
Mi Young AhnKi Ho Hong

Abstract

In view of this pandemic, as of February 2020, South Korea has the second highest number of confirmed cases in the world. Herein, we report four confirmed coronavirus disease 2019 (COVID-19) cases in the early stage of the pandemic in South Korea and describe the identification, diagnosis, clinical course, and management, including one patient's initial mild symptoms at presentation and their progression to pneumonia on day 21 of illness. Within 48 hours of hospitalization, all four patients underwent evaluation for initial laboratory parameters, COVID-19 polymerase chain reaction (PCR), and chest computed tomography (CT) findings. All four mild COVID-19 patients were discharged, and they were re-examined 14 days after discharge. Despite all four of them being asymptomatic, one patient was re-admitted after confirmation of COVID-19 through PCR viral nucleic acid detection. She could be discharged after 7 days with two subsequent negative COVID-19 PCR at 24-hour intervals. Patients with mild COVID-19 generally have normal follow-up chest CT scans after discharge, even if the early chest CT definitely indicates pneumonia. Re-hospitalized patients with COVID-19 PCR positive results after discharge were not related to her initial c...Continue Reading

References

Jan 30, 2020·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Victor M CormanChristian Drosten
Feb 8, 2020·JAMA : the Journal of the American Medical Association·Dawei WangZhiyong Peng
Feb 15, 2020·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Kyung Soo Lee
Feb 23, 2020·JAMA : the Journal of the American Medical Association·John E L WongChorh Chuan Tan
Jun 13, 2020·Osong Public Health and Research Perspectives·UNKNOWN Korea Centers for Disease Control and Prevention
Jun 27, 2020·Obstetrics and Gynecology·Ilia Bresesti, Lorella Rossi

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Citations

Apr 17, 2021·The Korean Journal of Internal Medicine·Hae-Young LeeUNKNOWN National Committee for Clinical Management of Emerging Infectious Diseases

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Methods Mentioned

BETA
PCR
nucleic acid amplification
X-ray

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