PMID: 16617190Apr 18, 2006Paper

Four cases of Graves' disease which developed after painful Hashimoto's thyroiditis

Internal Medicine
Hidemi OhyeAkira Miyauchi

Abstract

We report four cases of Graves' disease that developed after painful Hashimoto's thyroiditis. All were middle-aged women, who had high titers of anti-thyroid antibodies and thyrotoxicosis at the onset of painful Hashimoto's thyroiditis. After 2 to 7 years, they developed Graves' disease with positive antibody against the thyrotropin receptor. Their clinical courses of Graves' disease went favorably due to the treatment with antithyroid drug or radioactive iodine therapy. Painful Hashimoto's thyroiditis is an atypical variant of Hashimoto's thyroiditis and is one form of destructive thyroiditis. Thyroid damage due to painful Hashimoto's thyroiditis may be associated with the development of Graves' disease.

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Oct 11, 2008·Thyroid : Official Journal of the American Thyroid Association·Marian Ludgate, Charles H Emerson
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