Four hormones in the pancreas of the lizard, Anolis carolinensis

The Anatomical Record
W B Rhoten, C E Hall

Abstract

The electron microscopic localization of insulin, glucagon, somatostatin, and pancreatic polypeptide (PP) in the pancreas of the iguanid lizard, Anolis carolinensis was studied by the unlabeled antibody peroxidase-antiperoxidase immunocytochemical technique. Insulin, glucagon, and somatostatin were localized absolutely to those cells previously identified on the basis of the characteristics of their secretory granules as being beta cells, alpha cells, and D cells, respectively. The secretory granule cores of the PP-containing cells appeared to be ellipsoidal with a semi-major axis of 450 nm and a semi-minor axis of 365 nm. This previously unidentified cell type is named the F cell, in keeping with the localization of PP to the original F cell of the canine pancreas. Without immunocytochemical staining, the qualitative ultrastructural characteristics of the F cell secretory granules were inadequate to permit identification of the F cell, especially with regard to the D cell.

References

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Citations

Jan 22, 2000·General and Comparative Endocrinology·M T LozanoB Agulleiro
Sep 11, 1999·General and Comparative Endocrinology·J LópezA Martínez
Feb 1, 2014·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Kurt H Albertine, Scott C Miller
Nov 1, 1989·General and Comparative Endocrinology·R Perez-TomasJ M Polak
Jul 1, 1984·General and Comparative Endocrinology·W B RhotenS Christakos
Sep 1, 1989·General and Comparative Endocrinology·A Garcia AyalaB Agulleiro
Jun 5, 1998·General and Comparative Endocrinology·A J MichelmoreB Kramer

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