Four Subgroups of Blood Stasis Syndrome Are Identified by Manifestation Cluster Analysis in Males

Evidence-based Complementary and Alternative Medicine : ECAM
Sooseong YouMyeong Soo Lee

Abstract

Blood stasis syndrome (BSS) is an important pathological condition in traditional East Asian medicine and is associated with ischemic heart disease, cerebral vascular accident, diabetes mellitus, chronic renal failure, severe traumatic injury, and dysmenorrhea. However, previous studies have been unable to reveal the clinical and biological characteristics or biological markers of BSS. We hypothesized that the heterogeneity among the manifestations of BSS or non-BSS could interfere with an analysis to describe the characteristics of BSS. In this study, male participants based on the severity of BSS-associated symptoms and signs were clustered and classified into four subgroups: BSS subgroups (1), (2), (3), and (4). Non-BSS core subgroup was redefined using manifestation cluster analysis. Biological characteristics of subgroups BSS(1) and BSS(2) belong to the range of the non-BSS core subgroup (1), whereas that of subgroups BSS(3) and BSS(4) are characterized by different biological parameters such as systemic inflammatory conditions and elevated D-dimer level. Our results suggested that patients in subgroups of BSS(3) and BSS(4) are more likely to be exposed in an inflammatory state than other BSS subgroups. We found the hetero...Continue Reading

References

Jul 15, 2003·The American Journal of Chinese Medicine·Chih-Jui LoChing-Liang Hsieh
Mar 2, 2011·Chinese Journal of Integrative Medicine·Kui-Wu YaoJie Wang
Jul 24, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Ye HuangKe-Ji Chen
Aug 7, 2013·Chinese Journal of Integrative Medicine·Jie Wang, Gui Yu
Nov 28, 2013·Complementary Therapies in Medicine·Young-Jae ParkYoung-Bae Park
Dec 29, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Shuzhen GuoWei Wang
Mar 13, 2014·Chinese Journal of Integrative Medicine·Si-ming LiKe-ji Chen
Sep 5, 2014·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·Jodi C McDaniel, Kristine K Browning
Mar 31, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Bongki ParkMyeong Soo Lee
Jun 6, 2015·American Journal of Translational Research·Sooseong YouMyeong Soo Lee
Jun 30, 2016·Blood·Laura L Swystun, Patricia C Liaw
Sep 24, 2016·BMC Complementary and Alternative Medicine·Jiangquan LiaoJie Wang

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Methods Mentioned

BETA
ESR

Software Mentioned

Statistical Analysis System ( SAS

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