Fourier modeling of the BOLD response to a breath-hold task: Optimization and reproducibility

NeuroImage
Joana PintoPatricia Figueiredo

Abstract

Cerebrovascular reactivity (CVR) reflects the capacity of blood vessels to adjust their caliber in order to maintain a steady supply of brain perfusion, and it may provide a sensitive disease biomarker. Measurement of the blood oxygen level dependent (BOLD) response to a hypercapnia-inducing breath-hold (BH) task has been frequently used to map CVR noninvasively using functional magnetic resonance imaging (fMRI). However, the best modeling approach for the accurate quantification of CVR maps remains an open issue. Here, we compare and optimize Fourier models of the BOLD response to a BH task with a preparatory inspiration, and assess the test-retest reproducibility of the associated CVR measurements, in a group of 10 healthy volunteers studied over two fMRI sessions. Linear combinations of sine-cosine pairs at the BH task frequency and its successive harmonics were added sequentially in a nested models approach, and were compared in terms of the adjusted coefficient of determination and corresponding variance explained (VE) of the BOLD signal, as well as the number of voxels exhibiting significant BOLD responses, the estimated CVR values, and their test-retest reproducibility. The brain average VE increased significantly with t...Continue Reading

References

Jun 29, 1996·BMJ : British Medical Journal·J M Bland, D G Altman
Dec 4, 1998·Stroke; a Journal of Cerebral Circulation·A KastrupM E Moseley
Mar 10, 2001·Journal of Magnetic Resonance Imaging : JMRI·K NakadaS Yoshida
Sep 10, 2002·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Nikos K Logothetis
Oct 23, 2002·Human Brain Mapping·Stephen M Smith
Apr 6, 2005·NeuroImage·Moriah E ThomasonGary H Glover
May 4, 2006·Human Brain Mapping·Moriah E ThomasonGary H Glover
Nov 10, 2006·Human Brain Mapping·Daniel A HandwerkerMark D'Esposito
Jan 9, 2007·NeuroImage·Oleg Leontiev, Richard B Buxton
Jan 16, 2007·Arquivos de neuro-psiquiatria·Katia C AndradeDraulio B de Araujo
Apr 5, 2007·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Richard G WisePeter Jezzard
Oct 2, 2007·NeuroImage·Moriah E Thomason, Gary H Glover
Dec 1, 2007·Journal of Magnetic Resonance Imaging : JMRI·Eitan PrismanDavid Mikulis
Apr 16, 2008·NeuroImage·Kenneth P EatonScott K Holland
Jul 29, 2008·NeuroImage·Catie ChangGary H Glover
Feb 13, 2009·NeuroImage·Stefano MagonAndrea Sbarbati
Jan 1, 1997·Human Brain Mapping·O JosephsK Friston
Jul 22, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Clarisse I MarkG Bruce Pike
Oct 21, 2010·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Molly G BrightDaniel P Bulte
Apr 19, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Nicholas P BlockleyPenny A Gowland
Dec 16, 2011·World Journal of Clinical Oncology·Jay J Pillai, Domenico Zacá
May 1, 2012·Journal of Magnetic Resonance Imaging : JMRI·Felipe B TancrediRichard D Hoge
Aug 25, 2012·Radiology Research and Practice·Renata F LeoniOctavio M Pontes-Neto
Aug 28, 2012·Magnetic Resonance Imaging·João JorgeJosé P Marques
Apr 11, 2013·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Felipe B Tancredi, Richard D Hoge
Oct 2, 2013·The Journal of Physiology·J FierstraJ A Fisher
Mar 3, 2015·Journal of Magnetic Resonance Imaging : JMRI·Clarisse I MarkJ Jean Chen
Sep 4, 2015·Advances in Physiology Education·Rachel J SkowCraig D Steinback

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Citations

Sep 30, 2016·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Hesamoddin JahanianUNKNOWN SPRINT Study Research Group
Oct 13, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Joana PintoPatrícia Figueiredo
Mar 9, 2018·Frontiers in Neuroscience·Ilaria Boscolo GalazzoGloria Menegaz
Feb 5, 2021·Frontiers in Physiology·Joana PintoPatrícia Figueiredo
Nov 17, 2020·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Kamen A TsvetanovJames B Rowe
Nov 23, 2021·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Moss Y ZhaoGreg Zaharchuk

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