PMID: 9540765Apr 16, 1998Paper

Fournier's gangrene during induction treatment of acute promyelocytic leukemia, a case report

Annals of Hematology
V LévyR Zittoun

Abstract

Fournier's gangrene is described as a fulminant necrotizing fasciitis of the scrotum and penis. Few cases have been reported in the context of acute leukemia. We describe a case, complicating the induction treatment of an acute promyelocytic leukemia with all-trans-retinoic acid and chemotherapy. The evolution was favorable, following surgical excision and broad-spectrum antibiotic therapy. The respective roles of all-trans-retinoic acid and granulocytopenia are discussed. This devastating and life-threatening infection must be kept in mind for early clinical, bacteriological, and radiological diagnosis and surgical management.

Citations

Jan 24, 2004·Leukemia & Lymphoma·Kenji FukunoHisataka Moriwaki
May 18, 2001·Best Practice & Research. Clinical Haematology·P FenauxL Degos
Nov 16, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Scott GettingerMichael Grossbard
Sep 30, 2003·Medical and Pediatric Oncology·Chetna BakshiSuresh Advani
Jan 21, 2006·Pediatric Blood & Cancer·Elpis MantadakisGeorge Samonis
Aug 21, 2015·World Journal of Gastroenterology : WJG·Tomislav BruketaGoran Augustin
Sep 27, 2000·Diseases of the Colon and Rectum·R J YaghanI Bani-Hani
Dec 21, 2018·BMJ Case Reports·Vanessa Fiorini FurtadoJohn Mark Sloan
Jan 9, 2003·The Surgical Clinics of North America·Emilio Morpurgo, Susan Galandiuk
Feb 16, 2010·Cirugía española·Jose Torremadé BarredaSebastiano Biondo

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