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Foxp3 and IL-10 expression correlates with parasite burden in lesional tissues of post kala azar dermal leishmaniasis (PKDL) patients

PLoS Neglected Tropical Diseases

Jun 10, 2011

Gajendra Kumar KataraPoonam Salotra

Abstract

Post kala-azar dermal leishmaniasis (PKDL), a sequel to visceral leishamaniasis (VL) in 5-15% cases, constitutes a parasite reservoir important in disease transmission. The precise immunological cause of PKDL outcome remains obscure. However, overlapping counter regulatory responses wit...read more

Mentioned in this Paper

CD80 Antigens
Real-Time Polymerase Chain Reaction
FOXP3 protein, human
Immune Response
CD86 gene
IL2RA protein, human
T-Lymphocyte
Decreased Immunologic Activity [PE]
Genus: Leishmania
Leukocyte Differentiation Antigens, Human
43
Paper Details
References
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  • Citations31
123
  • References24
  • Citations31
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Foxp3 and IL-10 expression correlates with parasite burden in lesional tissues of post kala azar dermal leishmaniasis (PKDL) patients

PLoS Neglected Tropical Diseases

Jun 10, 2011

Gajendra Kumar KataraPoonam Salotra

PMID: 21655313

DOI: 10.1371/journal.pntd.0001171

Abstract

Post kala-azar dermal leishmaniasis (PKDL), a sequel to visceral leishamaniasis (VL) in 5-15% cases, constitutes a parasite reservoir important in disease transmission. The precise immunological cause of PKDL outcome remains obscure. However, overlapping counter regulatory responses wit...read more

Mentioned in this Paper

CD80 Antigens
Real-Time Polymerase Chain Reaction
FOXP3 protein, human
Immune Response
CD86 gene
IL2RA protein, human
T-Lymphocyte
Decreased Immunologic Activity [PE]
Genus: Leishmania
Leukocyte Differentiation Antigens, Human
43

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References24
  • Citations31
123
  • References24
  • Citations31
1234
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