Fracture Prediction by Computed Tomography and Finite Element Analysis: Current and Future Perspectives.

Current Osteoporosis Reports
Fjola JohannesdottirMary L Bouxsein

Abstract

This review critiques the ability of CT-based methods to predict incident hip and vertebral fractures. CT-based techniques with concurrent calibration all show strong associations with incident hip and vertebral fracture, predicting hip and vertebral fractures as well as, and sometimes better than, dual-energy X-ray absorptiometry areal biomass density (DXA aBMD). There is growing evidence for use of routine CT scans for bone health assessment. CT-based techniques provide a robust approach for osteoporosis diagnosis and fracture prediction. It remains to be seen if further technical advances will improve fracture prediction compared to DXA aBMD. Future work should include more standardization in CT analyses, establishment of treatment intervention thresholds, and more studies to determine whether routine CT scans can be efficiently used to expand the number of individuals who undergo evaluation for fracture risk.

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Citations

Nov 16, 2019·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M T LöfflerT Baum
Apr 27, 2020·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·T M KeavenyM L Bouxsein
Jun 24, 2020·International Journal of Legal Medicine·Olivier DubourgPauline Saint-Martin
Mar 12, 2020·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Da ZouZhongning Xu
Jul 14, 2020·Computer Methods in Biomechanics and Biomedical Engineering·Cristina Falcinelli, Cari Whyne
Jun 18, 2020·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Michael A KellyJohn J Carey

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