Fracture Rates and Bone Density Among Postmenopausal Veteran and Non-Veteran Women From the Women's Health Initiative

The Gerontologist
Joanne LaFleurAndrea Z LaCroix

Abstract

Postmenopausal osteoporosis can impact quality-of-life even prefracture. To determine whether osteoporosis should be a greater concern in women Veterans versus non-Veterans, we compared fracture rates and bone mineral density (BMD) for Veterans and non-Veterans using Women's Health Initiative data. In this cohort study, participants were women aged 50-79 years. Outcomes were hip, central body, and limb fractures occurring during up to 19 years of follow-up and hip, spine, and whole body BMD collected three times over a 6-year period in a participant subsample. Covariates comprised risk factors for fracture, including fall history and other components of the World Health Organization Fracture Risk Assessment Tool (FRAX). Cox Proportional Hazards models were used to examine fracture rates for Veterans compared with non-Veterans. Of 161,808 women, 145,521 self-identified as Veteran (n = 3,719) or non-Veteran (n = 141,802). Baseline FRAX scores showed that Veterans had higher 10-year probabilities for any major fracture (13.3 vs 10.2; p < .01) and hip fracture (4.1 vs 2.2; p < .01) compared with non-Veterans. The age-adjusted rate of hip fracture per 1,000 person-years for Veterans was 3.3 versus 2.4 for non-Veterans (p < .01). Aft...Continue Reading

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Citations

Jan 16, 2016·The Gerontologist·Lori A BastianElizabeth M Yano
Jan 11, 2017·Current Opinion in Rheumatology·Jane A Cauley
Feb 16, 2019·The Journal of Antimicrobial Chemotherapy·E Lerma-ChippirrazR Güerri-Fernández
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Sep 12, 2017·Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health·Karen M GoldsteinDonna L Washington

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