Fractures in a tertiary Neonatal Intensive Care Unit in Wales

Acta Paediatrica
Christina WeiJustin Warner

Abstract

To explore associations with fractures reported in a tertiary neonatal intensive care unit (NICU). Babies admitted to NICU from 1998 to 2007 in Cardiff, UK, with fractures during admission were identified. Clinical information was extracted from inpatient records. Results were reported as median (ranges). Seventy-one fractures were recorded in 27 (boys = 16) infants with a gestational age of 28 (23.6-40.4) weeks and birthweight of 920 g (485-4875). Fractures were recognized at 57 (1-128) days of age. Neonates with fractures without clear aetiologies (n = 17) were more preterm (p < 0.001), were born lighter (p < 0.001), required multiple medical interventions, were more commonly osteopenic (p < 0.001), had fractures detected later (p < 0.001) and had more posterior rib fractures (p = 0.009). Rib fractures were detected later than other sites (p = 0.002). Associations with rib fractures included osteopenia (p = 0.04), longer oxygen therapy (p = 0.018), length on total parental nutrition (p = 0.03), later achievement of full enteral feeds (p = 0.038), sepsis (p = 0.038) and surgical procedures (p = 0.004). Posterior rib fractures were more common in babies born more preterm (25.1 vs. 29.4 weeks, p = 0.003) and requiring diuretics ...Continue Reading

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Citations

Sep 17, 2014·Child Abuse & Neglect·Howard DubowitzNancy D Kellogg
Feb 26, 2016·Hospital Pediatrics·Lisa Swartz ToporSusanna Y Huh
Feb 23, 2017·AJR. American Journal of Roentgenology·Cindy W Christian, Lisa J States
Mar 12, 2020·Journal of Paediatrics and Child Health·Peter O'ReillyNaomi McCallion
Feb 16, 2013·Journal of Pediatric Endocrinology & Metabolism : JPEM·Colin R Paterson, Elizabeth A Monk
Mar 2, 2018·The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG·Lucas E Orth, Keliana L O'Mara
Oct 20, 2017·Journal of Paediatrics and Child Health·Mary WhitePeter J Simm
Oct 7, 2020·Children·Vito PavoneGianluca Testa
Mar 1, 2021·Journal of Pediatric Endocrinology & Metabolism : JPEM·Ulf Högberg, Ingemar Thiblin
Sep 20, 2016·The Journal of Steroid Biochemistry and Molecular Biology·John Jacob Cannell, Michael F Holick

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