Frailty Assessment in Advanced Heart Failure

Journal of Cardiac Failure
Shivank A MadanSnehal R Patel

Abstract

Several studies have recently demonstrated the value of frailty assessment in a general heart failure (HF) population; however, it is unknown whether these findings are also applicable in advanced HF. We investigated the utility of frailty assessment and its prognostic value in elderly patients with advanced HF. Forty consecutive elderly subjects aged ≥65 years, with left ventricular ejection fraction ≤35%, New York Heart Association class III or IV, and a 6-minute walk test <300 m were enrolled from the HF clinic at Montefiore Medical Center between October 2012 and July 2013. Subjects were assessed for frailty with the Fried Frailty Index, consisting of 5 components: hand grip strength, 15-foot walk time, weight loss, physical activity, and exhaustion. All subjects were prospectively followed for death or hospitalization. At baseline, the mean age of the cohort was 74.9 ± 6.5 years, 58% female, left ventricular ejection fraction 25.6 ± 6.4%, 6-minute walk test 195.8 ± 74.3 m and length of follow-up 454 ± 186 days. Thirty-five percent were prefrail and 65% were frail. Frailty status was associated with the combined primary endpoint of mortality and all-cause hospitalization (hazard ratio [HR] 1.93, 95% confidence interval [CI]...Continue Reading

References

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Citations

Aug 2, 2016·The Canadian Journal of Cardiology·Hoda Butrous, Scott L Hummel
Aug 2, 2016·The Canadian Journal of Cardiology·Naheed RajabaliSean M Bagshaw
May 5, 2017·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Julee McDonaghPhillip J Newton
Mar 31, 2017·Current Treatment Options in Cardiovascular Medicine·Susan M Joseph, Michael W Rich
Sep 25, 2017·Journal of the American Geriatrics Society·Mathew S MaurerGordon R Reeves
Aug 11, 2019·Journal of the American Geriatrics Society·Ersilia M DeFilippisVeli K Topkara
Mar 4, 2020·ESC Heart Failure·Emma E F KleipoolMajon Muller
Jul 18, 2020·Journal of Clinical Medicine·Klara KomiciErmanno Eleuteri
Oct 4, 2020·Journal of Clinical Medicine·Amitai SegevGad Segal
Dec 21, 2018·Journal of the American Heart Association·Xiaobo YangErik Fung
Jul 2, 2020·International Journal of Chronic Obstructive Pulmonary Disease·Lara de Souza DiasMarcelo Fouad Rabahi
Mar 4, 2021·International Journal of Cardiology·Mary Roberts DavisQuin E Denfeld
Aug 8, 2021·Journal of Clinical Medicine·Amaury BroussierThibaud Damy
May 26, 2021·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·Michitaka KatoShingo Omote
Aug 26, 2021·Heart & Lung : the Journal of Critical Care·Sarah E SchroederWindy W Alonso

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