Frailty state transitions and associated factors in South Australian older adults

Geriatrics & Gerontology International
Mark Q ThompsonRenuka Visvanathan

Abstract

Frailty is a state of decreased physiological reserve and vulnerability to stressors. Understanding the characteristics of those most at risk of worsening, or likely to improve their frailty status, are key elements in addressing this condition. The present study measured frailty state transitions and factors associated with improvement or worsening frailty status in the North West Adelaide Health Study. Frailty was measured using the frailty phenotype (FP) and a 34-item frailty index (FI) for 696 community-dwelling participants aged ≥65 years, with repeated measures at 4.5-year follow up. Improvement in frailty state was common for both tools (FP 15.5%; FI 7.9%). The majority remained stable (FP 44.4%; FI 52.6%), and many transitioned to a worse level of frailty (FP 40.1%; FI 39.5%). For both measures, multimorbidity was associated with worsening frailty among non-frail participants. Among pre-frail participants, normal waist circumference was associated with improvement, whereas older age was associated with worsening of frailty status. Among frail individuals, younger age was associated with improvement, and male sex and older age were associated with worsening frailty status. Frailty is a dynamic process where improvement i...Continue Reading

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Citations

Jul 19, 2019·Journal of the American Geriatrics Society·Mark Q ThompsonRenuka Visvanathan
Sep 12, 2019·PloS One·Hossein Haji Ali AfzaliRenuka Visvanathan
Mar 4, 2020·International Journal of Environmental Research and Public Health·Tan Van NguyenTu Ngoc Nguyen
Aug 5, 2020·Australasian Journal on Ageing·Mark Q ThompsonRenuka Visvanathan
Aug 11, 2020·The Medical Journal of Australia·Jyoti KhadkaMaria C Inacio
May 13, 2020·Current HIV/AIDS Reports·Julian Falutz
Jun 16, 2021·Journal of the American Medical Directors Association·Bing-Ru DongZhi-Gang Pan
Jul 16, 2019·Journal of the American Medical Directors Association·Gotaro KojimaKate Walters
Aug 15, 2021·Journal of the American Medical Directors Association·Ángel Rodríguez-LasoLeocadio Rodríguez-Mañas

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