Frailty status at admission to hospital predicts multiple adverse outcomes

Age and Ageing
R E HubbardKenneth Rockwood

Abstract

frailty is proposed as a summative measure of health status and marker of individual vulnerability. We aimed to investigate the discriminative capacity of a frailty index (FI) derived from interRAI Comprehensive Geriatric Assessment for Acute Care (AC) in relation to multiple adverse inpatient outcomes. in this prospective cohort study, an FI was derived for 1,418 patients ≥70 years across 11 hospitals in Australia. The interRAI-AC was administered at admission and discharge by trained nurses, who also screened patients daily for geriatric syndromes. in adjusted logistic regression models an increase of 0.1 in FI was significantly associated with increased likelihood of length of stay >28 days (odds ratio [OR]: 1.29 [1.10-1.52]), new discharge to residential aged care (OR: 1.31 [1.10-1.57]), in-hospital falls (OR: 1.29 [1.10-1.50]), delirium (OR: 2.34 [2.08-2.63]), pressure ulcer incidence (OR: 1.51 [1.23-1.87]) and inpatient mortality (OR: 2.01 [1.66-2.42]). For each of these adverse outcomes, the cut-point at which optimal sensitivity and specificity occurred was for an FI > 0.40. Specificity was higher than sensitivity with positive predictive values of 7-52% and negative predictive values of 88-98%. FI-AC was not significan...Continue Reading

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Citations

Jan 5, 2018·Age and Ageing·Alison M Mudge, Ruth E Hubbard
Jul 7, 2018·Acta Anaesthesiologica Scandinavica·K M Hillman
Sep 22, 2018·Journal of the American Geriatrics Society·Ilaria PersicoGiuseppe Bellelli
Aug 14, 2018·QJM : Monthly Journal of the Association of Physicians·K J GregorevicR E Hubbard
Sep 28, 2018·Aging Clinical and Experimental Research·Chi-Wen ChengWen-Jin Cherng
Jan 12, 2019·Journal of Evaluation in Clinical Practice·Xin Ying ChuaShiou Liang Wee
Jan 28, 2018·BMC Geriatrics·Jordi Amblàs-NovellasRoman Romero-Ortuno
Aug 10, 2018·Internal Medicine Journal·Leo KyiLynden J Roberts
Sep 16, 2018·BMC Cancer·A L McCarthyR E Hubbard
Sep 12, 2019·PloS One·Hossein Haji Ali AfzaliRenuka Visvanathan
Dec 12, 2019·Hospital Practice·Wil L SantivasiKevin J Whitford
Dec 31, 2019·The Medical Journal of Australia·Emily H Gordon, Ruth E Hubbard
Feb 25, 2020·Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society·Erwin StolzChristian Jagsch
May 7, 2020·Age and Ageing·Ruth E HubbardKenneth Rockwood
Sep 10, 2020·Journal of the American Geriatrics Society·Beatriz León-SalasPedro Serrano-Aguilar
Oct 2, 2019·International Journal of Environmental Research and Public Health·Rónán O'CaoimhJohn O'Donnell
Jan 20, 2019·Journal of Biomedical Semantics·Kristina Doing-HarrisCharlene Weir
Dec 20, 2019·Advances in Skin & Wound Care·Jeffrey M Levine
Jan 27, 2019·Internal Medicine Journal·Alison M Mudge, Ruth E Hubbard
Jul 17, 2019·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Eilís KeebleSimon Paul Conroy
Feb 14, 2020·International Journal for Equity in Health·Sudeh Cheraghi-SohiCaroline Sanders
Jun 6, 2018·British Medical Bulletin·L J NeilsonC J Rees
Aug 7, 2019·QJM : Monthly Journal of the Association of Physicians·S ClarkT Frakking
Oct 7, 2020·The Kaohsiung Journal of Medical Sciences·Wendy ChaboyerLaurie Grealish
Oct 30, 2020·Australasian Journal on Ageing·Katherine BloomfieldMartin J Connolly
Nov 6, 2020·Journal of the American Geriatrics Society·Janani ThillainadesanVasi Naganathan
Nov 24, 2020·Journal of Women's Health·Hoang T PhanDominique A Cadilhac
Oct 20, 2020·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Rebecca Abey-NesbitHamish A Jamieson
Feb 24, 2021·Age and Ageing·Simon Conroy, Matt Thomas
Dec 18, 2020·Annals of Emergency Medicine·Amy ElliottSimon Conroy
May 22, 2021·Clinical Journal of Oncology Nursing·Sherry L RaftersLinda Lillington

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