FRAX (Aus) and falls risk: Association in men and women

Bone
K L HollowayJulie Anne Pasco

Abstract

The WHO fracture risk prediction tool (FRAX®) utilises clinical risk factors to estimate the probability of fracture over a 10-year period. Although falls increase fracture risk, they have not been incorporated into FRAX. It is currently unclear if FRAX captures falls risk and whether addition of falls would improve fracture prediction. We aimed to investigate the association of falls risk and Australian-specific FRAX. Clinical risk factors were documented for 735 men and 602 women (age 40-90 yr) assessed at follow-up (2006-2010 and 2000-2003, respectively) of the Geelong Osteoporosis Study. FRAX scores with and without BMD were calculated. A falls risk score was determined at the time of BMD assessment and self-reported incident falls were documented from questionnaires returned one year later. Multivariable analyses were performed to determine: (i) cross-sectional association between FRAX scores and falls risk score (Elderly Falls Screening Test, EFST) and (ii) prospective relationship between FRAX and time to a fall. There was an association between FRAX (hip with BMD) and EFST scores (β = 0.07, p < 0.001). After adjustment for sex and age, the relationship became non-significant (β = 0.00, p = 0.79). The risk of incident fa...Continue Reading

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Citations

Aug 19, 2015·Archives of Gerontology and Geriatrics·Pingda BianZhangxuan Shou
Aug 5, 2015·Current Opinion in Clinical Nutrition and Metabolic Care·Catherine CormierJean-Claude Souberbielle
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May 31, 2018·Physiotherapy Theory and Practice·Patricia A DowneyDavid P Thompson

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