Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity⁻Brief Review

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Piotr MinkiewiczMałgorzata Darewicz

Abstract

Diet is considered to be a significant factor in cancer prevention and therapy. Many food components reveal anticancer activity. The increasing number of experiments concerning the anticancer potential of chemical compounds, including food components, is a challenge for data searching. Specialized databases provide an opportunity to overcome this problem. Data concerning the anticancer activity of chemical compounds may be found in general databases of chemical compounds and databases of drugs, including specialized resources concerning anticancer compounds, databases of food components, and databases of individual groups of compounds, such as polyphenols or peptides. This brief review summarizes the state of knowledge of chemical databases containing information concerning natural anticancer compounds (e.g., from food). Additionally, the information about text- and structure-based search options and links between particular internet resources is provided in this paper. Examples of the application of databases in food and nutrition sciences are also presented with special attention to compounds that are interesting from the point of view of dietary cancer prevention. Simple examples of potential database search possibilities ar...Continue Reading

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Citations

Dec 1, 2019·International Journal of Molecular Sciences·Piotr MinkiewiczMałgorzata Darewicz
Jan 23, 2020·Expert Opinion on Drug Discovery·Karina Martinez-MayorgaGerald Maggiora
Feb 13, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Piotr MinkiewiczMarta Turło

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Software Mentioned

JSME Lookup
ChemSpider
Google Scholar
OpenTargets
OmicTools
BIOPEP
BRENDA
MetaComBio
ChemRTP
PubChem

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