PMID: 9540301Apr 16, 1998Paper

Free radicals in inflammatory neurological disease: increased lipid peroxidation and haptoglobin levels in Guillain Barré syndrome

Irish Journal of Medical Science
N J GutowskiR P Murphy

Abstract

Oxidative damage in three inflammatory neurological disorders; Guillain Barré syndrome (GBS), multiple sclerosis and aseptic meningitis, were assessed by measuring the peroxidation of lipids in body fluids. The results were compared to a control group consisting of patients with either migraine, chronic/tension headaches, benign intracranial hypertension or psychological disorders. Antioxidant status was assessed by the measurement of the extracellular proteins, haptoglobin, albumin, caeruloplasmin and transferrin. The results of the study suggested that firstly, haptoglobin levels might be a useful, easily obtainable marker to aid the diagnosis of GBS. Secondly, free radical damage may be implicated in the pathology of GBS and therefore appropriate free radical scavenging might have beneficial effects.

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Citations

Nov 9, 2000·Clinical Chemistry and Laboratory Medicine : CCLM·M A Abou-SeifM Nasr
Apr 18, 2007·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·T JinJ Zhu
Mar 3, 2007·The Journal of Pharmacy and Pharmacology·Mohammed M H Al-GayyarAmal M El-Gayar
Jul 17, 2004·Clinica Chimica Acta; International Journal of Clinical Chemistry·Kiran T KumarAnjali Rao
Jun 12, 2008·Arquivos de neuro-psiquiatria·Leonardo H Mendonça OliveiraMaria de Fátima Sonati
Apr 1, 2017·Expert Review of Proteomics·Ping JinEdouard C Nice
Dec 3, 2005·Multiple Sclerosis : Clinical and Laboratory Research·G FerrettiL Provinciali
Feb 16, 1999·Brain Pathology·K J SmithP A Felts
Jul 16, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Monika Adamczyk-SowaKrystyna Pierzchała
May 8, 2020·Journal of Neuroinflammation·Thomas GrüterKalliopi Pitarokoili
Nov 27, 2020·Frontiers in Neurology·Chuxin HuangWei Lu

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