PMID: 3768368Nov 6, 1986Paper

Free volume model for lipid lateral diffusion coefficients. Assessment of the temperature dependence in phosphatidylcholine and phosphatidylethanolamine bilayers

Biochimica Et Biophysica Acta
M D King, Derek Marsh

Abstract

The lipid lateral diffusion coefficients, DT, in fluid-phase phosphatidylcholine and phosphatidylethanolamine bilayers have been analysed in terms of the free-volume diffusion model by fitting the expression: DT = AT exp[- B/(T - T0)] to the observed temperature dependence, where A, B and T0 are the parameters to be optimized. Application of an unconstrained optimization procedure to data obtained from excimer formation (Galla et al. (1979) J. Membrane Biol. 48, 215-236) and from fluorescence photobleaching (Vaz et al. (1985) Biochemistry 24, 781-786) provides statistical evidence for a free-volume model as opposed to a simple Stokes-Einstein model (T0 = 0), only in certain cases. In the instances for which the parameter T0 can be determined with a reasonable degree of accuracy, it is found that this characteristic temperature at which the free volume extrapolates to zero lies below the bilayer gel-to-fluid phase transition temperature and does not coincide with the pre-transition temperature for phosphatidylcholines.

References

Jul 31, 1979·The Journal of Membrane Biology·H J GallaE Sackmann
Aug 1, 1978·Biophysical Journal·J F Nagle, D A Wilkinson
Aug 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·P G Saffman, M Delbrück
Jun 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·C J CornbrooksR P Bunge

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Citations

May 15, 2013·Biochimica Et Biophysica Acta·Derek MarshMikael Esmann
Oct 15, 2011·Biophysical Chemistry·Petra PullmannováDaniela Uhríková
Jun 11, 2004·Biophysical Journal·Vincent Schram, Stephen B Hall
Sep 27, 2016·Langmuir : the ACS Journal of Surfaces and Colloids·Yoshiaki OkamotoRyugo Tero

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