Freehand diffuse optical spectroscopy imaging for intraoperative identification of major venous and arterial vessels underlying peritoneal fat: an in vivo demonstration in a pig model

Journal of Biomedical Optics
Daqing PiaoSanjay G Patel

Abstract

Inadvertent injury to important anatomic structures is a significant risk in minimally invasive surgery (MIS) that potentially requires conversion to an open procedure, which results in increased morbidity and mortality. Surgeons operating minimal-invasively currently do not have an easy-to-use, real-time device to aid in intraoperative identification of important anatomic structures that underlie tissue planes. We demonstrate freehand diffuse optical spectroscopy (DOS) imaging for intraoperatively identifying major underlying veins and arteries. An applicator probe that can be affixed to and detached from an 8-mm laparoscopic instrument has been developed. The 10-mm DOS source-detector separation renders sampling of tissue heterogeneities a few millimeters deep. DOS spectra acquired consecutively during freehand movement of the applicator probe on the tissue surface are displayed as a temporal and spectral image to assist in spatially resolved identification of the underlying structures. Open surgery identifications of the vena cava and aorta underlying peritoneal fat of ∼4  mm in thickness using the applicator probe under room light were demonstrated repeatedly in multiple pigs in vivo.

References

Mar 17, 2005·Cardiovascular and Interventional Radiology·Rafael F PeriniDavid Adams
Dec 17, 2014·American Journal of Obstetrics and Gynecology·Matthew T SiedhoffThomas Ivester
Feb 1, 2015·Japanese Journal of Clinical Oncology·Kazuyuki YugeMototsugu Oya
May 20, 2015·World Journal of Clinical Cases·Sergio Fernández-Pello MontesJavier Mosquera Madera

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Citations

Aug 31, 2018·Journal of Biomedical Optics·Daqing PiaoErin M Rubin

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