Freezing of gait and affective theory of mind in Parkinson disease

Parkinsonism & Related Disorders
Alessia Raffo De FerrariLaura Avanzino

Abstract

Affective "Theory of Mind" (ToM) is the specific ability to represent own and others' emotional states and feelings. Several studies examined affective ToM ability in patients with Parkinson's disease (PD), using the "Reading the Mind in the Eyes test" (RMET). However, there has been no agreement as to whether or not affective ToM ability is impaired in PD and such discrepancy may be due to the heterogeneous clinical presentation of PD. Affective disturbance has been linked to the akinetic-rigid form of PD and to gait disturbances, like freezing of gait (FOG). Particularly, FOG has been associated with dysfunction in striatum ability of processing affective inputs. Here we hypothesized that the presence of FOG can be associated with impaired affective ToM ability in PD patients. We evaluated ToM by means of RMET and executive functions using the Tower Of London (ToL) test in 29 PD patients (15 with FOG and 14 without FOG) and 19 healthy age-matched subjects. Our results showed that affective ToM is abnormal in PD patients, compared to healthy subjects and that it is more impaired in patients with FOG than in patients without FOG. Further, PD patients with FOG performed worse than PD patients without FOG on the ToL test. The aff...Continue Reading

References

Mar 31, 2001·Journal of Child Psychology and Psychiatry, and Allied Disciplines·S Baron-CohenI Plumb
Feb 20, 2003·Neuropsychologia·J S SnowdenD Neary
Nov 17, 2006·Psychiatry Research·Simone G Shamay-TsooryYechiel Levkovitz
Jul 21, 2007·Neuropsychologia·Simone G Shamay-Tsoory, Judith Aharon-Peretz
Dec 15, 2007·Journal of the International Neuropsychological Society : JINS·J UekermannI Daum
Jan 29, 2009·Experimental Aging Research·Matteo Pardini, Paolo F Nichelli
Jan 18, 2011·Behavioural Brain Research·Michele PolettiMauro Adenzato
Jul 23, 2011·Lancet Neurology·John G NuttAlice Nieuwboer
Aug 2, 2011·Neuropsychologia·Ahmad Abu-Akel, Simone Shamay-Tsoory
Nov 3, 2012·Journal of Neurology, Neurosurgery, and Psychiatry·Matteo PardiniLeonardo Cocito
May 21, 2013·Psychiatry and Clinical Neurosciences·Michele PolettiUbaldo Bonuccelli
Feb 12, 2014·JAMA Neurology·Mary Ann Thenganatt, Joseph Jankovic
Jun 20, 2014·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Olga Dal MonteFrank Krueger
Jan 8, 2015·Frontiers in Psychiatry·Michael James WeightmanBernhard Theodor Baune

❮ Previous
Next ❯

Citations

Feb 13, 2016·Accident; Analysis and Prevention·Jennifer GeraghtyKim Rochelle
Oct 25, 2016·Gait & Posture·Marianna CapecciMaria Gabriella Ceravolo
Oct 31, 2018·Scientific Reports·Rwei-Ling YuChun-Hsiang Tan
Jan 4, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Ota GalEvzen Ruzicka
Jun 6, 2020·Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration·Tom BurkeNiall Pender
Aug 24, 2019·Movement Disorders : Official Journal of the Movement Disorder Society·Ota GálEvžen Růžička
Aug 10, 2020·Journal of Neural Transmission·Giovanna LagravineseLaura Avanzino
Jun 2, 2018·Progress in Neuro-psychopharmacology & Biological Psychiatry·Clare M Eddy, Jennifer L Cook
Jan 29, 2021·Parkinson's Disease·Ana Natalia Seubert-RaveloAdela Hernández-Galván
Aug 7, 2020·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Beatrice OrsoMatteo Pardini
Mar 25, 2021·Brain and Cognition·Maria Alice BaraldiGiovanna Lagravinese

❮ Previous
Next ❯

Related Concepts

Related Feeds

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

Basal ganglia in Parkinson's disease (MDS)

The basal ganglia is comprised of the neostriatum, the external and internal pallidal segments, the subthalamic nucleus, the substantia nigra pars reticulata, and the pars compacta of the substantia nigra. The basal ganglia circuitry is responsible for the correct execution of voluntary movements and is implicated in Parkinson's disease. Here is the latest research investigating the basal ganglia in Parkinson's disease.

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Related Papers

Parkinsonism & Related Disorders
Natsuko TsuruyaMitsuru Kawamura
Neurorehabilitation and Neural Repair
Jochen VandenbosscheEric Kerckhofs
Psychiatry and Clinical Neurosciences
Michele PolettiUbaldo Bonuccelli
© 2021 Meta ULC. All rights reserved