Frequency and Impact of Adverse Events in Patients Undergoing Surgery for End-Stage Ankle Arthritis

Foot & Ankle International
Daniel C NorvellBruce J Sangeorzan

Abstract

This study summarized the frequency and functional impact of adverse events (AEs) that occur after surgery for end-stage ankle arthritis (ESAA) to inform decision making. This was a multisite prospective cohort study to compare ankle arthroplasty to ankle arthrodesis in the treatment of ESAA among 6 participating sites. We compared the risk and impact of nonankle AEs and ankle-specific AEs versus no AEs controlling for potential confounding factors, including operative procedure using multinomial logistic regression. We estimated differences in postoperative functional outcomes by AE occurrence using linear mixed effects regression. Among 517 patients who had surgery for ankle arthritis and completed the full baseline assessment, follow-up scores were available in 494 (95%) patients. There were a total of 628 reported AEs (477 in the arthroplasty group and 151 in the arthrodesis group). These occurred in 261 (63%) arthroplasty patients and 67 (65%) arthrodesis patients. There were 50 (8%) ankle-specific AEs. The risk of an ankle-specific AE was slightly higher in the arthrodesis group versus the arthroplasty group, odds ratio (OR) 1.84, 95% confidence interval (CI, 0.85, 3.98). The OR for the risk of non-ankle-specific AE versu...Continue Reading

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Citations

Aug 23, 2019·The Journal of Bone and Joint Surgery. American Volume·Daniel C NorvellBruce J Sangeorzan
Jun 6, 2020·Foot & Ankle International·William L JohnsTyler A Gonzalez
Jan 11, 2019·Foot & Ankle International·Leah GuichardValeria Martinez
Jul 6, 2019·The Journal of Bone and Joint Surgery. American Volume·Jane B ShoferBruce J Sangeorzan
Oct 10, 2019·The Journal of Bone and Joint Surgery. American Volume·Gun-Woo Lee, Keun-Bae Lee
Mar 27, 2021·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Nihar S ShahRichard Laughlin
May 14, 2021·The Journal of Bone and Joint Surgery. American Volume·Bruce J SangeorzanDaniel C Norvell
Jun 6, 2021·Foot and Ankle Surgery : Official Journal of the European Society of Foot and Ankle Surgeons·A MazzottiC Faldini
Aug 8, 2021·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Stein B M van den HeuvelTim Schepers

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Software Mentioned

ggplot2
multcomp
nnet
lme4
Stata
lsmeans
R

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