Frequency and risk factors of postoperative recurrence of Crohn's disease after intestinal resection in the Chinese population.

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Yi LiJieshou Li

Abstract

Data on risk factors of postoperative recurrence in patients with Crohn's disease (CD) have shown conflicting results. The aim of this retrospective study is to identify predictors of early symptomatic recurrence of CD after surgical intestinal resection in the Chinese population. Patients diagnosed as CD who underwent intestinal resection in Jinling Hospital between May 2004 and December 2010 were included in our study. Clinical data of these patients were reviewed. Multivariable survival analysis was performed to elucidate risk factors of early postoperative symptomatic recurrence. There were a total of 141 CD patients who had at least one previous curative resection for CD under regular follow-up in our unit. Our data indicated disease behavior (95 % CI 1.01-1.70, P = 0.044), smoking habits (95 % CI 1.32-2.84, P = 0.001), indication of perforation (95 % CI 1.09-4.02, P = 0.026), and location of anastomosis (95 % CI 1.09-3.39, P = 0.023) which are, as a result, strong independent predictors of symptomatic recurrence, while the anastomosis type as side-to-side anastomosis (SSA) was significantly associated with a decreased risk of symptomatic recurrence when compared with other anastomosis type (95 % CI 0.26-0.94, P = 0.038). ...Continue Reading

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Citations

Apr 24, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Takayuki Yamamoto
Oct 26, 2016·Gastroenterology Research and Practice·Dong GuoWeiming Zhu
Nov 22, 2016·World Journal of Gastrointestinal Pharmacology and Therapeutics·Pei-Qi WangSusan Hutfless
Jun 19, 2014·Scandinavian Journal of Gastroenterology·Yi LiJieshou Li
Oct 14, 2014·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Yi LiJieshou Li
Jun 27, 2019·Current Drug Targets·Kalle LanderholmPär Myrelid
Oct 2, 2021·Clinical and Translational Gastroenterology·Yipeng ZhuWeiming Zhu

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